An Analysis of Long-Term Quality of Life Changes in Uveal Melanoma Patients Depending on Age and Treatment Type
We analyze long-term changes of quality of life (QOL) in uvealmelanoma patients, depending on age and treatment type. The study involved 100 patients (28 males and 72 females) aged 11 to 79. The patients were divided in three age groups: group I (25 years or younger), II (26-59 years), III (over 60...
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Real Time Ltd
2018-10-01
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| Series: | Российский офтальмологический журнал |
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| Online Access: | https://roj.igb.ru/jour/article/view/9 |
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| author | S. V. Saakyan A. G. Amiryan I. S. Mironova |
| author_facet | S. V. Saakyan A. G. Amiryan I. S. Mironova |
| author_sort | S. V. Saakyan |
| collection | DOAJ |
| description | We analyze long-term changes of quality of life (QOL) in uvealmelanoma patients, depending on age and treatment type. The study involved 100 patients (28 males and 72 females) aged 11 to 79. The patients were divided in three age groups: group I (25 years or younger), II (26-59 years), III (over 60 years), each group being further subdivided into subgroups depending on the treatment type - eye-preserving therapy (laser or brachytherapy) and enucleation. We used the general type questionnaire SF-36 for oncological patients. For each patient, the survey was taken once, 18 to 72 months after treatment start. The follow-up start median was 30 months for group 1 and 48 months for groups 2 and 3. It could be revealed that over the whole set of patients, the mean values of QOL parameters are no worse than the similar parameters in healthy population. No statistically significant differences in QOL parameters of patients from Groups 1 and 2 were revealed between those receiving eye-preserving or enucleation (p > 0.05). In group 3 statistically significant differences were found in the scales of physical and emotional functioning (p = 0.014, p = 0.001). Middle-aged and elderly patients who received laser treatment demonstrated a higher QOL level as compared to patients of the same age categories who received brachytherapy. In particular, group 2 patients revealed statistically significant differences in the scales of general health (GH, p = 0.012) and vitality (VT, p = 0.03), whereas the patients of group 3 showed similar differences in the scales of GH (p = 0.043), physical functioning (p = 0.005), bodily pain (BP, p = 0.003) and VT (p = 0,048). The lowest levels of QOL were identified in elderly patients after enucleation, and the best results were achieved in patients after laser treatment in all age groups // Russian Ophthalmological Journal, 2016; 1: 56-61. |
| format | Article |
| id | doaj-art-9b04a2f17c1a4b728bb6313c90313ea8 |
| institution | Kabale University |
| issn | 2072-0076 2587-5760 |
| language | Russian |
| publishDate | 2018-10-01 |
| publisher | Real Time Ltd |
| record_format | Article |
| series | Российский офтальмологический журнал |
| spelling | doaj-art-9b04a2f17c1a4b728bb6313c90313ea82025-08-20T03:39:45ZrusReal Time LtdРоссийский офтальмологический журнал2072-00762587-57602018-10-0191566110.21516/2072-0076-2016-9-1-56-619An Analysis of Long-Term Quality of Life Changes in Uveal Melanoma Patients Depending on Age and Treatment TypeS. V. Saakyan0A. G. Amiryan1I. S. Mironova2Helmholtz Research Institute of Eye Diseases, Moscow, RussiaHelmholtz Research Institute of Eye Diseases, Moscow, RussiaHelmholtz Research Institute of Eye Diseases, Moscow, RussiaWe analyze long-term changes of quality of life (QOL) in uvealmelanoma patients, depending on age and treatment type. The study involved 100 patients (28 males and 72 females) aged 11 to 79. The patients were divided in three age groups: group I (25 years or younger), II (26-59 years), III (over 60 years), each group being further subdivided into subgroups depending on the treatment type - eye-preserving therapy (laser or brachytherapy) and enucleation. We used the general type questionnaire SF-36 for oncological patients. For each patient, the survey was taken once, 18 to 72 months after treatment start. The follow-up start median was 30 months for group 1 and 48 months for groups 2 and 3. It could be revealed that over the whole set of patients, the mean values of QOL parameters are no worse than the similar parameters in healthy population. No statistically significant differences in QOL parameters of patients from Groups 1 and 2 were revealed between those receiving eye-preserving or enucleation (p > 0.05). In group 3 statistically significant differences were found in the scales of physical and emotional functioning (p = 0.014, p = 0.001). Middle-aged and elderly patients who received laser treatment demonstrated a higher QOL level as compared to patients of the same age categories who received brachytherapy. In particular, group 2 patients revealed statistically significant differences in the scales of general health (GH, p = 0.012) and vitality (VT, p = 0.03), whereas the patients of group 3 showed similar differences in the scales of GH (p = 0.043), physical functioning (p = 0.005), bodily pain (BP, p = 0.003) and VT (p = 0,048). The lowest levels of QOL were identified in elderly patients after enucleation, and the best results were achieved in patients after laser treatment in all age groups // Russian Ophthalmological Journal, 2016; 1: 56-61.https://roj.igb.ru/jour/article/view/9увеальная меланомакачество жизниотдаленные результатыuveal melanomaquality of lifelong-term results |
| spellingShingle | S. V. Saakyan A. G. Amiryan I. S. Mironova An Analysis of Long-Term Quality of Life Changes in Uveal Melanoma Patients Depending on Age and Treatment Type Российский офтальмологический журнал увеальная меланома качество жизни отдаленные результаты uveal melanoma quality of life long-term results |
| title | An Analysis of Long-Term Quality of Life Changes in Uveal Melanoma Patients Depending on Age and Treatment Type |
| title_full | An Analysis of Long-Term Quality of Life Changes in Uveal Melanoma Patients Depending on Age and Treatment Type |
| title_fullStr | An Analysis of Long-Term Quality of Life Changes in Uveal Melanoma Patients Depending on Age and Treatment Type |
| title_full_unstemmed | An Analysis of Long-Term Quality of Life Changes in Uveal Melanoma Patients Depending on Age and Treatment Type |
| title_short | An Analysis of Long-Term Quality of Life Changes in Uveal Melanoma Patients Depending on Age and Treatment Type |
| title_sort | analysis of long term quality of life changes in uveal melanoma patients depending on age and treatment type |
| topic | увеальная меланома качество жизни отдаленные результаты uveal melanoma quality of life long-term results |
| url | https://roj.igb.ru/jour/article/view/9 |
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