Perspectives on the current diagnostic and treatment paradigms in secondary hemophagocytic lymphohistiocytosis (HLH)

Perspectives on the current diagnostic and treatment paradigms in secondary hemophagocytic lymphohistiocytosis (HLH)

Abstract Improved awareness of hemophagocytic lymphohistiocytosis (HLH) among clinicians has led to an increase in its diagnosis. Often diagnosis is made based on the HLH- 2004 criteria. While these criteria have considerable strengths, they lack specificity and may be fulfilled in the setting of ma...

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Main Authors: Leonard Naymagon, Philip Roehrs, Michelle Hermiston, James Connelly, Jeffrey Bednarski, Jaap-Jan Boelens, Shanmuganathan Chandrakasan, Blachy Dávila Saldaña, Michael M. Henry, Prakash Satwani, Anish Ray, Kelly Walkovich, David Teachey, Edward M. Behrens, Scott W. Canna, Ashish Kumar
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Orphanet Journal of Rare Diseases
Online Access:https://doi.org/10.1186/s13023-025-03698-0
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