Antibacterial carbon dots
Bacterial infections significantly threaten human health, leading to severe diseases and complications across multiple systems and organs. Antibiotics remain the primary treatment strategy for these infections. However, the growing resistance of bacteria to conventional antibiotics underscores the u...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-02-01
|
| Series: | Materials Today Bio |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590006424004447 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850025064220590080 |
|---|---|
| author | Shuaishuai Wang Dapeng Wang Guoliang Wang Minglei Zhang Yirong Sun Jianxun Ding |
| author_facet | Shuaishuai Wang Dapeng Wang Guoliang Wang Minglei Zhang Yirong Sun Jianxun Ding |
| author_sort | Shuaishuai Wang |
| collection | DOAJ |
| description | Bacterial infections significantly threaten human health, leading to severe diseases and complications across multiple systems and organs. Antibiotics remain the primary treatment strategy for these infections. However, the growing resistance of bacteria to conventional antibiotics underscores the urgent need for safe and effective alternative treatments. In response, several approaches have been developed, including carbon dots (CDs), antimicrobial peptides, and antimicrobial polymers, all of which have proven effective in combating bacterial resistance. Among these, CDs stand out due to their unique advantages, including low preparation cost, stable physicochemical properties, high biocompatibility, tunable surface chemistry, strong photoluminescence, and efficient generation of reactive oxygen species. These features make CDs highly promising in antibacterial applications. This review explores the development of antibacterial CDs, focusing on their mechanisms of action—physical destroy, biochemical damage, and synergistic effects—while highlighting their potential for clinical use as antibacterial agents. |
| format | Article |
| id | doaj-art-9af4548e904a49feb6ab7bca97507aa1 |
| institution | DOAJ |
| issn | 2590-0064 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Materials Today Bio |
| spelling | doaj-art-9af4548e904a49feb6ab7bca97507aa12025-08-20T03:00:57ZengElsevierMaterials Today Bio2590-00642025-02-013010138310.1016/j.mtbio.2024.101383Antibacterial carbon dotsShuaishuai Wang0Dapeng Wang1Guoliang Wang2Minglei Zhang3Yirong Sun4Jianxun Ding5Department of Orthopedic Surgery, China-Japan Union Hospital of Jilin University, 126 Xiantai Street, Changchun 130033, PR China; Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun 130022, PR ChinaSchool of Mechanical and Aerospace Engineering, Jilin University, 5988 Renmin Street, Changchun 130033, PR ChinaKey Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun 130022, PR ChinaDepartment of Orthopedic Surgery, China-Japan Union Hospital of Jilin University, 126 Xiantai Street, Changchun 130033, PR China; Corresponding author.Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun 130022, PR China; Corresponding author.Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun 130022, PR China; School of Applied Chemistry and Engineering, University of Science and Technology of China, 96 Jinzhai Road, Hefei 230026, PR ChinaBacterial infections significantly threaten human health, leading to severe diseases and complications across multiple systems and organs. Antibiotics remain the primary treatment strategy for these infections. However, the growing resistance of bacteria to conventional antibiotics underscores the urgent need for safe and effective alternative treatments. In response, several approaches have been developed, including carbon dots (CDs), antimicrobial peptides, and antimicrobial polymers, all of which have proven effective in combating bacterial resistance. Among these, CDs stand out due to their unique advantages, including low preparation cost, stable physicochemical properties, high biocompatibility, tunable surface chemistry, strong photoluminescence, and efficient generation of reactive oxygen species. These features make CDs highly promising in antibacterial applications. This review explores the development of antibacterial CDs, focusing on their mechanisms of action—physical destroy, biochemical damage, and synergistic effects—while highlighting their potential for clinical use as antibacterial agents.http://www.sciencedirect.com/science/article/pii/S2590006424004447Carbon dotAntibacterial performancePhysical destroyBiochemical damageSynergistic effect |
| spellingShingle | Shuaishuai Wang Dapeng Wang Guoliang Wang Minglei Zhang Yirong Sun Jianxun Ding Antibacterial carbon dots Materials Today Bio Carbon dot Antibacterial performance Physical destroy Biochemical damage Synergistic effect |
| title | Antibacterial carbon dots |
| title_full | Antibacterial carbon dots |
| title_fullStr | Antibacterial carbon dots |
| title_full_unstemmed | Antibacterial carbon dots |
| title_short | Antibacterial carbon dots |
| title_sort | antibacterial carbon dots |
| topic | Carbon dot Antibacterial performance Physical destroy Biochemical damage Synergistic effect |
| url | http://www.sciencedirect.com/science/article/pii/S2590006424004447 |
| work_keys_str_mv | AT shuaishuaiwang antibacterialcarbondots AT dapengwang antibacterialcarbondots AT guoliangwang antibacterialcarbondots AT mingleizhang antibacterialcarbondots AT yirongsun antibacterialcarbondots AT jianxunding antibacterialcarbondots |