The relationship between dietary phytochemical index and risk of gestational diabetes mellitus in Iran: a case–control study

Abstract Background The risk of developing gestational diabetes mellitus has been linked to dietary factors. This is one of the first studies that has investigated the relationship between dietary phytochemical index (DPI) and gestational diabetes mellitus (GDM). This study was conducted with the ai...

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Main Authors: Tooba Bahramfard, Mohammad-Amin Zolghadrpour, Mohammad-Reza Jowshan, Davood Sheikhi, Atousa Zandvakili, Zahra Mohagheghzade, Marjan Roozbehi, Azizollah Pourmahmoudi
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Nutrition
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Online Access:https://doi.org/10.1186/s40795-025-01070-w
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author Tooba Bahramfard
Mohammad-Amin Zolghadrpour
Mohammad-Reza Jowshan
Davood Sheikhi
Atousa Zandvakili
Zahra Mohagheghzade
Marjan Roozbehi
Azizollah Pourmahmoudi
author_facet Tooba Bahramfard
Mohammad-Amin Zolghadrpour
Mohammad-Reza Jowshan
Davood Sheikhi
Atousa Zandvakili
Zahra Mohagheghzade
Marjan Roozbehi
Azizollah Pourmahmoudi
author_sort Tooba Bahramfard
collection DOAJ
description Abstract Background The risk of developing gestational diabetes mellitus has been linked to dietary factors. This is one of the first studies that has investigated the relationship between dietary phytochemical index (DPI) and gestational diabetes mellitus (GDM). This study was conducted with the aim of investigating the relationship between DPI and GDM. Methods This case–control study investigated 71 women without GDM and 71 women with GDM who had a singleton fetus. The average age of these two groups was 28 and 33 years, respectively, and these pregnant mothers were in the 27th week of pregnancy on average. A 168-item semi-quantitative FFQ questionnaire was used to determine food intake. Then, to check the intake status of dietary phytochemicals, DPI was calculated, then logistic regression was used in different models to evaluate the relationship between DPI and GDM. Results After adjusting for confounding factors, participants in the highest DPI tertile had 88% less chance of developing GDM (odds ratio = 0.12; 95% confidence intervals: 0.86–0.019). The mean DPI score of the case and control groups were 31.01 ± 22.17 and 36.09 ± 8.73, respectively. The overall mean DPI score for the study was 33.59 ± 18.88. Conclusion Women who have a higher DPI score are less likely to develop GDM, but more studies are necessary to confirm the results of the present study.
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spelling doaj-art-9aed1b74b75d42ed993edbe9e9f299952025-08-20T01:59:56ZengBMCBMC Nutrition2055-09282025-05-0111111010.1186/s40795-025-01070-wThe relationship between dietary phytochemical index and risk of gestational diabetes mellitus in Iran: a case–control studyTooba Bahramfard0Mohammad-Amin Zolghadrpour1Mohammad-Reza Jowshan2Davood Sheikhi3Atousa Zandvakili4Zahra Mohagheghzade5Marjan Roozbehi6Azizollah Pourmahmoudi7Students Research Committee, Lorestan University of Medical SciencesDepartment of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical SciencesDepartment of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical SciencesDepartment of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical SciencesFaculty of Literature and Human Sciences, Persian Gulf UniversityStudent Research Committee, Yasuj University of Medical SciencesDepartment of Nutrition, Science and Research Branch, Islamic Azad UniversityDepartment of Nutrition, School of Health & Nutrition, Yasuj University of Medical SciencesAbstract Background The risk of developing gestational diabetes mellitus has been linked to dietary factors. This is one of the first studies that has investigated the relationship between dietary phytochemical index (DPI) and gestational diabetes mellitus (GDM). This study was conducted with the aim of investigating the relationship between DPI and GDM. Methods This case–control study investigated 71 women without GDM and 71 women with GDM who had a singleton fetus. The average age of these two groups was 28 and 33 years, respectively, and these pregnant mothers were in the 27th week of pregnancy on average. A 168-item semi-quantitative FFQ questionnaire was used to determine food intake. Then, to check the intake status of dietary phytochemicals, DPI was calculated, then logistic regression was used in different models to evaluate the relationship between DPI and GDM. Results After adjusting for confounding factors, participants in the highest DPI tertile had 88% less chance of developing GDM (odds ratio = 0.12; 95% confidence intervals: 0.86–0.019). The mean DPI score of the case and control groups were 31.01 ± 22.17 and 36.09 ± 8.73, respectively. The overall mean DPI score for the study was 33.59 ± 18.88. Conclusion Women who have a higher DPI score are less likely to develop GDM, but more studies are necessary to confirm the results of the present study.https://doi.org/10.1186/s40795-025-01070-wDietary phytochemical indexGestational diabetes mellitusPregnancyIran
spellingShingle Tooba Bahramfard
Mohammad-Amin Zolghadrpour
Mohammad-Reza Jowshan
Davood Sheikhi
Atousa Zandvakili
Zahra Mohagheghzade
Marjan Roozbehi
Azizollah Pourmahmoudi
The relationship between dietary phytochemical index and risk of gestational diabetes mellitus in Iran: a case–control study
BMC Nutrition
Dietary phytochemical index
Gestational diabetes mellitus
Pregnancy
Iran
title The relationship between dietary phytochemical index and risk of gestational diabetes mellitus in Iran: a case–control study
title_full The relationship between dietary phytochemical index and risk of gestational diabetes mellitus in Iran: a case–control study
title_fullStr The relationship between dietary phytochemical index and risk of gestational diabetes mellitus in Iran: a case–control study
title_full_unstemmed The relationship between dietary phytochemical index and risk of gestational diabetes mellitus in Iran: a case–control study
title_short The relationship between dietary phytochemical index and risk of gestational diabetes mellitus in Iran: a case–control study
title_sort relationship between dietary phytochemical index and risk of gestational diabetes mellitus in iran a case control study
topic Dietary phytochemical index
Gestational diabetes mellitus
Pregnancy
Iran
url https://doi.org/10.1186/s40795-025-01070-w
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