A review on anti-aging actions of plant polysaccharides

Aging can lead to a decline in the biological functions of the body's cells and tissues, triggering various chronic diseases, including cardiovascular disease, diabetes, and neurodegenerative disorders. This gradual weakening of the body increases the risk of mortality. With societal advancemen...

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Main Authors: Ranran Huang, Ruihan Li, Meihui Qin, Nina Qian, Keng Po Lai, Huiling Lu, Rong Li
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:Future Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666833525001467
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author Ranran Huang
Ruihan Li
Meihui Qin
Nina Qian
Keng Po Lai
Huiling Lu
Rong Li
author_facet Ranran Huang
Ruihan Li
Meihui Qin
Nina Qian
Keng Po Lai
Huiling Lu
Rong Li
author_sort Ranran Huang
collection DOAJ
description Aging can lead to a decline in the biological functions of the body's cells and tissues, triggering various chronic diseases, including cardiovascular disease, diabetes, and neurodegenerative disorders. This gradual weakening of the body increases the risk of mortality. With societal advancements and improvements in modern medical standards, there is a growing focus on anti-aging research, prompting an urgent search for effective anti-aging therapies. Plant polysaccharides possess numerous natural pharmacological effects, including anti-aging, anti-inflammatory, immune regulation, anti-tumor properties, and blood sugar reduction. Additionally, plant polysaccharides are associated with minimal toxic side effects and high safety profiles, while being widely sourced from various plants. Owing to these natural advantages, plant polysaccharides have become a research hotspot across multiple fields. Specifically, plant polysaccharides can modulate aging through mechanisms such as enhancing antioxidant enzyme activity, regulating inflammatory factors, promoting cell autophagy and division, improving mitochondrial function, increasing telomerase activity, and regulating gut microbiota. Thus, they play a significant role and hold an important position in the field of anti-aging research. This article briefly reviews the mechanisms of aging and the progress made in understanding the anti-aging effects of plant polysaccharides, providing a reference for further investigation in this area.
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publisher Elsevier
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series Future Foods
spelling doaj-art-9aecf34f873b43aeb7b941b7f247aeb52025-08-20T02:10:03ZengElsevierFuture Foods2666-83352025-12-011210068410.1016/j.fufo.2025.100684A review on anti-aging actions of plant polysaccharidesRanran Huang0Ruihan Li1Meihui Qin2Nina Qian3Keng Po Lai4Huiling Lu5Rong Li6Key Laboratory of Environmental Pollution and Integrative Omics, Education Department of Guangxi Zhuang Autonomous Region, Guilin Medical University, Guilin, China; Lingui Clinical College of Guilin Medical University, Guilin, ChinaKey Laboratory of Environmental Pollution and Integrative Omics, Education Department of Guangxi Zhuang Autonomous Region, Guilin Medical University, Guilin, ChinaKey Laboratory of Environmental Pollution and Integrative Omics, Education Department of Guangxi Zhuang Autonomous Region, Guilin Medical University, Guilin, ChinaKey Laboratory of Environmental Pollution and Integrative Omics, Education Department of Guangxi Zhuang Autonomous Region, Guilin Medical University, Guilin, ChinaDepartment of Applied Science, School of Science and Technology, Hong Kong Metropolitan University, Hong Kong SAR, China; Corresponding author at: Department of Applied Science, School of Science and Technology, Hong Kong Metropolitan University, Ho Man Tin, Hong Kong SAR, China.Key Laboratory of Environmental Pollution and Integrative Omics, Education Department of Guangxi Zhuang Autonomous Region, Guilin Medical University, Guilin, China; Corresponding author at: Key Laboratory of Environmental Pollution and Integrative Omics, Education Department of Guangxi Zhuang Autonomous Region, Guilin Medical University, No. 1 Zhiyuan Road, Lingui District, Guilin 541199, China.Key Laboratory of Environmental Pollution and Integrative Omics, Education Department of Guangxi Zhuang Autonomous Region, Guilin Medical University, Guilin, China; Corresponding author at: Key Laboratory of Environmental Pollution and Integrative Omics, Education Department of Guangxi Zhuang Autonomous Region, Guilin Medical University, No. 1 Zhiyuan Road, Lingui District, Guilin 541199, China.Aging can lead to a decline in the biological functions of the body's cells and tissues, triggering various chronic diseases, including cardiovascular disease, diabetes, and neurodegenerative disorders. This gradual weakening of the body increases the risk of mortality. With societal advancements and improvements in modern medical standards, there is a growing focus on anti-aging research, prompting an urgent search for effective anti-aging therapies. Plant polysaccharides possess numerous natural pharmacological effects, including anti-aging, anti-inflammatory, immune regulation, anti-tumor properties, and blood sugar reduction. Additionally, plant polysaccharides are associated with minimal toxic side effects and high safety profiles, while being widely sourced from various plants. Owing to these natural advantages, plant polysaccharides have become a research hotspot across multiple fields. Specifically, plant polysaccharides can modulate aging through mechanisms such as enhancing antioxidant enzyme activity, regulating inflammatory factors, promoting cell autophagy and division, improving mitochondrial function, increasing telomerase activity, and regulating gut microbiota. Thus, they play a significant role and hold an important position in the field of anti-aging research. This article briefly reviews the mechanisms of aging and the progress made in understanding the anti-aging effects of plant polysaccharides, providing a reference for further investigation in this area.http://www.sciencedirect.com/science/article/pii/S2666833525001467Aging mechanismPlant polysaccharideAntisenescence
spellingShingle Ranran Huang
Ruihan Li
Meihui Qin
Nina Qian
Keng Po Lai
Huiling Lu
Rong Li
A review on anti-aging actions of plant polysaccharides
Future Foods
Aging mechanism
Plant polysaccharide
Antisenescence
title A review on anti-aging actions of plant polysaccharides
title_full A review on anti-aging actions of plant polysaccharides
title_fullStr A review on anti-aging actions of plant polysaccharides
title_full_unstemmed A review on anti-aging actions of plant polysaccharides
title_short A review on anti-aging actions of plant polysaccharides
title_sort review on anti aging actions of plant polysaccharides
topic Aging mechanism
Plant polysaccharide
Antisenescence
url http://www.sciencedirect.com/science/article/pii/S2666833525001467
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