The Influence of Type-1 Diabetes Mellitus on Central Corneal Thickness in Children
Objectives: To evaluate the central corneal thickness (CCT) in children with diabetes mellitus (DM), to compare the results with those of age- and sex-matched healthy subjects, and to assess the presence of any relationship between the disease-variable parameters and CCT. Materials and Methods: Th...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2014-12-01
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| Series: | Türk Oftalmoloji Dergisi |
| Subjects: | |
| Online Access: | http://www.oftalmoloji.org/article_7544/The-Influence-Of-Type-1-Diabetes-Mellitus-On-Central-Corneal-Thickness-In-Children |
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| Summary: | Objectives: To evaluate the central corneal thickness (CCT) in children with diabetes mellitus (DM), to compare the results with those
of age- and sex-matched healthy subjects, and to assess the presence of any relationship between the disease-variable parameters and CCT.
Materials and Methods: This prospective, cross-sectional study included 138 eyes of 138 subjects. The CCT was measured by
ultrasonic pachymetry in 66 children with type-1 DM and in 72 healthy subjects. The effects of the duration of DM, current hemoglobin
A1c levels (HbA1c), and fasting blood glucose (FBG) levels on CCT were also evaluated.
Results: The demographic characteristics of the study and control groups were similar (p>0.05). The average CCT was greater in the
study (555.2±38.6 µm) than in the control group (547.7±31.5 µm), but the difference was not statistically significant (independent
t-test, p=0.211). CCT was also not significantly different in children with diabetes >5 years’ duration (554.6±39.3 µm) compared to
diabetes ≤5 years’ duration (555.6±38.6 µm) (p>0.05), and there was no significant correlation between the CCT- and the DM-related
parameters in the study group (p>0.05).
Conclusion: Our findings indicate that DM does not affect the corneal thickness in adolescents. We also did not find any significant
correlation between disease-related variables and the CCT. (Turk J Ophthalmol 2014; 44: 445-8) |
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| ISSN: | 1300-0659 2147-2661 |