Colonic transendoscopic enteral tubing is revolutionizing intestinal therapeutics, diagnosis, and microbiome research

The intestine, as a crucial organ of the human body, has remained enigmatic despite the remarkable advancements in modern medical technology. Over the past decades, the invention of endoscopic technology has made the noninvasive intervention of the intestine a reality, expanding diagnostic and thera...

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Main Authors: Zheyu Wang, Xia Wu, Yaxue Wang, Quan Wen, Bota Cui, Faming Zhang
Format: Article
Language:English
Published: SAGE Publishing 2024-11-01
Series:Therapeutic Advances in Gastroenterology
Online Access:https://doi.org/10.1177/17562848241301574
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author Zheyu Wang
Xia Wu
Yaxue Wang
Quan Wen
Bota Cui
Faming Zhang
author_facet Zheyu Wang
Xia Wu
Yaxue Wang
Quan Wen
Bota Cui
Faming Zhang
author_sort Zheyu Wang
collection DOAJ
description The intestine, as a crucial organ of the human body, has remained enigmatic despite the remarkable advancements in modern medical technology. Over the past decades, the invention of endoscopic technology has made the noninvasive intervention of the intestine a reality, expanding diagnostic and therapeutic options for diseases. However, due to the single-treatment feature of endoscopic procedures, continuous or repeated medication administration, sampling, and decompression drainage within the intestine have yet to be fulfilled. These limitations persisted until the invention of colonic transendoscopic enteral tubing (TET) in 2014, which realized repeated fecal microbiota transplantation, medication administration, and decompression drainage for the treatment of colon perforation and intestinal obstruction, as well as in situ dynamic sampling. These breakthroughs have not gone unnoticed, gaining global attention and recommendations from guidelines and consensuses. TET has emerged as a novel microbial research tool that offers new paradigms for human microbiome research. This review aims to update the research progress based on TET.
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id doaj-art-9ae5c6b152e64c77a89b2e5153f47636
institution OA Journals
issn 1756-2848
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publishDate 2024-11-01
publisher SAGE Publishing
record_format Article
series Therapeutic Advances in Gastroenterology
spelling doaj-art-9ae5c6b152e64c77a89b2e5153f476362025-08-20T02:32:52ZengSAGE PublishingTherapeutic Advances in Gastroenterology1756-28482024-11-011710.1177/17562848241301574Colonic transendoscopic enteral tubing is revolutionizing intestinal therapeutics, diagnosis, and microbiome researchZheyu WangXia WuYaxue WangQuan WenBota CuiFaming ZhangThe intestine, as a crucial organ of the human body, has remained enigmatic despite the remarkable advancements in modern medical technology. Over the past decades, the invention of endoscopic technology has made the noninvasive intervention of the intestine a reality, expanding diagnostic and therapeutic options for diseases. However, due to the single-treatment feature of endoscopic procedures, continuous or repeated medication administration, sampling, and decompression drainage within the intestine have yet to be fulfilled. These limitations persisted until the invention of colonic transendoscopic enteral tubing (TET) in 2014, which realized repeated fecal microbiota transplantation, medication administration, and decompression drainage for the treatment of colon perforation and intestinal obstruction, as well as in situ dynamic sampling. These breakthroughs have not gone unnoticed, gaining global attention and recommendations from guidelines and consensuses. TET has emerged as a novel microbial research tool that offers new paradigms for human microbiome research. This review aims to update the research progress based on TET.https://doi.org/10.1177/17562848241301574
spellingShingle Zheyu Wang
Xia Wu
Yaxue Wang
Quan Wen
Bota Cui
Faming Zhang
Colonic transendoscopic enteral tubing is revolutionizing intestinal therapeutics, diagnosis, and microbiome research
Therapeutic Advances in Gastroenterology
title Colonic transendoscopic enteral tubing is revolutionizing intestinal therapeutics, diagnosis, and microbiome research
title_full Colonic transendoscopic enteral tubing is revolutionizing intestinal therapeutics, diagnosis, and microbiome research
title_fullStr Colonic transendoscopic enteral tubing is revolutionizing intestinal therapeutics, diagnosis, and microbiome research
title_full_unstemmed Colonic transendoscopic enteral tubing is revolutionizing intestinal therapeutics, diagnosis, and microbiome research
title_short Colonic transendoscopic enteral tubing is revolutionizing intestinal therapeutics, diagnosis, and microbiome research
title_sort colonic transendoscopic enteral tubing is revolutionizing intestinal therapeutics diagnosis and microbiome research
url https://doi.org/10.1177/17562848241301574
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