Molecular Diagnostic Tests for Microsporidia

The Microsporidia are a ubiquitous group of eukaryotic obligate intracellular parasites which were recognized over 100 years ago with the description of Nosema bombycis, a parasite of silkworms. It is now appreciated that these organisms are related to the Fungi. Microsporidia infect all major anima...

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Main Authors: Kaya Ghosh, Louis M. Weiss
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Interdisciplinary Perspectives on Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2009/926521
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author Kaya Ghosh
Louis M. Weiss
author_facet Kaya Ghosh
Louis M. Weiss
author_sort Kaya Ghosh
collection DOAJ
description The Microsporidia are a ubiquitous group of eukaryotic obligate intracellular parasites which were recognized over 100 years ago with the description of Nosema bombycis, a parasite of silkworms. It is now appreciated that these organisms are related to the Fungi. Microsporidia infect all major animal groups most often as gastrointestinal pathogens; however they have been reported from every tissue and organ, and their spores are common in environmental sources such as ditch water. Several different genera of these organisms infect humans, but the majority of infections are due to either Enterocytozoon bieneusi or Encephalitozoon species. These pathogens can be difficult to diagnose, but significant progress has been made in the last decade in the development of molecular diagnostic reagents for these organisms. This report reviews the molecular diagnostic tests that have been described for the identification of the microsporidia that infect humans.
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spelling doaj-art-9ae3905eef6d4ef6954b9cfed8a865252025-08-20T03:36:57ZengWileyInterdisciplinary Perspectives on Infectious Diseases1687-708X1687-70982009-01-01200910.1155/2009/926521926521Molecular Diagnostic Tests for MicrosporidiaKaya Ghosh0Louis M. Weiss1Department of Pathology, Albert Einstein College of Medicine, Bronx, NY 10461, USADepartment of Pathology, Albert Einstein College of Medicine, Bronx, NY 10461, USAThe Microsporidia are a ubiquitous group of eukaryotic obligate intracellular parasites which were recognized over 100 years ago with the description of Nosema bombycis, a parasite of silkworms. It is now appreciated that these organisms are related to the Fungi. Microsporidia infect all major animal groups most often as gastrointestinal pathogens; however they have been reported from every tissue and organ, and their spores are common in environmental sources such as ditch water. Several different genera of these organisms infect humans, but the majority of infections are due to either Enterocytozoon bieneusi or Encephalitozoon species. These pathogens can be difficult to diagnose, but significant progress has been made in the last decade in the development of molecular diagnostic reagents for these organisms. This report reviews the molecular diagnostic tests that have been described for the identification of the microsporidia that infect humans.http://dx.doi.org/10.1155/2009/926521
spellingShingle Kaya Ghosh
Louis M. Weiss
Molecular Diagnostic Tests for Microsporidia
Interdisciplinary Perspectives on Infectious Diseases
title Molecular Diagnostic Tests for Microsporidia
title_full Molecular Diagnostic Tests for Microsporidia
title_fullStr Molecular Diagnostic Tests for Microsporidia
title_full_unstemmed Molecular Diagnostic Tests for Microsporidia
title_short Molecular Diagnostic Tests for Microsporidia
title_sort molecular diagnostic tests for microsporidia
url http://dx.doi.org/10.1155/2009/926521
work_keys_str_mv AT kayaghosh moleculardiagnostictestsformicrosporidia
AT louismweiss moleculardiagnostictestsformicrosporidia