In vitro activity of aztreonam in combination with relebactam against gram-negative pathogens producing various serine and metallo-β-lactamases

In vitro activity of aztreonam in combination with relebactam against gram-negative pathogens producing various serine and metallo-β-lactamases

Objectives: Infections caused by carbapenemase-producing Gram-negative pathogens have become a significant global public health challenge due to limited treatment options. Pathogens producing metallo-β-lactamase are particularly problematic since they are not inhibited by conventional β-lactamase in...

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Bibliographic Details
Main Authors: Kengo Hayashi, Masahiro Suzuki, Yoshikazu Ishii, Yasufumi Matsumura, Kazuaki Matsumoto, Sho Saito, Yohei Doi
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Aztreonam
Relebactam
Metallo-β-lactamase
Serine‑β-lactamase
Carbapenemase-producing pathogens
Co-producers
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716525000396
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