The Critical Role of Inhibitor of Differentiation 4 in Breast Cancer: From Mammary Gland Development to Tumor Progression

The Critical Role of Inhibitor of Differentiation 4 in Breast Cancer: From Mammary Gland Development to Tumor Progression

ABSTRACT Inhibitor of differentiation 4 (ID4) is a highly conserved DNA‐binding inhibitory protein of mammals, and its main role is to bind basic helix–loop–helix (b‐HLH) so that it loses its DNA‐binding activity, which in turn regulates the transcription of key genes, regulating cell differentiatio...

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Bibliographic Details
Main Authors: Yuhang Song, Panshi Zhang, Sudhanshu Bhushan, Xinhong Wu, Hongmei Zheng, Yalong Yang
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Cancer Medicine
Subjects:
breast cancer
development
ID4
mammary gland
Online Access:https://doi.org/10.1002/cam4.70856
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