Good long-term results of sacral neuromodulation for endometriosis related chronic pelvic pain

Abstract Background Sacral neuromodulation (SNM) is an established therapy in urology and gastroenterological surgery for treatment of overactive bladder symptoms, urge urinary incontinence or fecal incontinence. SNM has also been used with good results in patients with chronic pelvic pain (CPP). Ou...

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Main Authors: Adrian Zegrea, Emilia Ojala, Jaan Kirss, Pia Suvitie, Pirita Varpe, Johanna Mäkelä-Kaikkonen, Tero Rautio, Jaana Seikkula, Mika Ukkonen, Maija Lavonius, Tarja Pinta
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Women's Health
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Online Access:https://doi.org/10.1186/s12905-025-03699-y
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author Adrian Zegrea
Emilia Ojala
Jaan Kirss
Pia Suvitie
Pirita Varpe
Johanna Mäkelä-Kaikkonen
Tero Rautio
Jaana Seikkula
Mika Ukkonen
Maija Lavonius
Tarja Pinta
author_facet Adrian Zegrea
Emilia Ojala
Jaan Kirss
Pia Suvitie
Pirita Varpe
Johanna Mäkelä-Kaikkonen
Tero Rautio
Jaana Seikkula
Mika Ukkonen
Maija Lavonius
Tarja Pinta
author_sort Adrian Zegrea
collection DOAJ
description Abstract Background Sacral neuromodulation (SNM) is an established therapy in urology and gastroenterological surgery for treatment of overactive bladder symptoms, urge urinary incontinence or fecal incontinence. SNM has also been used with good results in patients with chronic pelvic pain (CPP). Our aim was to analyze long-term results of SNM in Finnish patients with endometriosis related CPP. Methods This is a register-based retrospective study including all the endometriosis patients treated with SNM for CPP in Finland between 2004 and 2017. There were four centers where these procedures were performed, two University Hospitals and two Central Hospitals. Long-term results were assessed by phone interview in spring 2021. Results A total of 16 women with endometriosis, with a median age of 39 (25–50) years, underwent SNM treatment for chronic pelvic pain (CPP), with the median follow-up time of 73 (48–85) months. The Implantable Pulse Generator (IPG) was implanted to 14 patients (88%). By the end of the follow-up period, 10 patients (62,5% of all patients and 71% of those who received IPG) had a functional SNM. Pain was assessed by numeral rating scale (NRS) and decreased from a median of 7.4 (3.6–10) to 2.3 (0-6.5). Conclusions SNM could be a good option in the treatment of endometriosis related chronic pelvic pain when standard therapy is not enough.
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spelling doaj-art-9ad15dff1f214a3cb6cd4972a26d9efb2025-08-20T03:10:18ZengBMCBMC Women's Health1472-68742025-04-012511610.1186/s12905-025-03699-yGood long-term results of sacral neuromodulation for endometriosis related chronic pelvic painAdrian Zegrea0Emilia Ojala1Jaan Kirss2Pia Suvitie3Pirita Varpe4Johanna Mäkelä-Kaikkonen5Tero Rautio6Jaana Seikkula7Mika Ukkonen8Maija Lavonius9Tarja Pinta10Seinäjoki Central HospitalTurku University Hospital and University of TurkuNorth Estonian Medical CentreTurku University Hospital and University of TurkuTurku University Hospital and University of TurkuOulu University HospitalOulu University HospitalJyväskylä Central HospitalJyväskylä Central HospitalTurku University Hospital and University of TurkuSeinäjoki Central HospitalAbstract Background Sacral neuromodulation (SNM) is an established therapy in urology and gastroenterological surgery for treatment of overactive bladder symptoms, urge urinary incontinence or fecal incontinence. SNM has also been used with good results in patients with chronic pelvic pain (CPP). Our aim was to analyze long-term results of SNM in Finnish patients with endometriosis related CPP. Methods This is a register-based retrospective study including all the endometriosis patients treated with SNM for CPP in Finland between 2004 and 2017. There were four centers where these procedures were performed, two University Hospitals and two Central Hospitals. Long-term results were assessed by phone interview in spring 2021. Results A total of 16 women with endometriosis, with a median age of 39 (25–50) years, underwent SNM treatment for chronic pelvic pain (CPP), with the median follow-up time of 73 (48–85) months. The Implantable Pulse Generator (IPG) was implanted to 14 patients (88%). By the end of the follow-up period, 10 patients (62,5% of all patients and 71% of those who received IPG) had a functional SNM. Pain was assessed by numeral rating scale (NRS) and decreased from a median of 7.4 (3.6–10) to 2.3 (0-6.5). Conclusions SNM could be a good option in the treatment of endometriosis related chronic pelvic pain when standard therapy is not enough.https://doi.org/10.1186/s12905-025-03699-yEndometriosisChronic pelvic painSacral neuromodulation
spellingShingle Adrian Zegrea
Emilia Ojala
Jaan Kirss
Pia Suvitie
Pirita Varpe
Johanna Mäkelä-Kaikkonen
Tero Rautio
Jaana Seikkula
Mika Ukkonen
Maija Lavonius
Tarja Pinta
Good long-term results of sacral neuromodulation for endometriosis related chronic pelvic pain
BMC Women's Health
Endometriosis
Chronic pelvic pain
Sacral neuromodulation
title Good long-term results of sacral neuromodulation for endometriosis related chronic pelvic pain
title_full Good long-term results of sacral neuromodulation for endometriosis related chronic pelvic pain
title_fullStr Good long-term results of sacral neuromodulation for endometriosis related chronic pelvic pain
title_full_unstemmed Good long-term results of sacral neuromodulation for endometriosis related chronic pelvic pain
title_short Good long-term results of sacral neuromodulation for endometriosis related chronic pelvic pain
title_sort good long term results of sacral neuromodulation for endometriosis related chronic pelvic pain
topic Endometriosis
Chronic pelvic pain
Sacral neuromodulation
url https://doi.org/10.1186/s12905-025-03699-y
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