Laboratory model to evaluate efficacy of an experimental titanium oxide nanofibers bleaching agent
ObjectivesThis study aimed to use a laboratory model to evaluate the efficacy of an experimental bleaching agent.Materials and MethodsThe model used human extracted molars that were treated and measured for bleaching efficacy. Teeth (n = 50) were distributed into 5 groups: Negative control (NC): imm...
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| Language: | English |
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Korean Academy of Conservative Dentistry
2021-11-01
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| Series: | Restorative Dentistry & Endodontics |
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| Online Access: | http://rde.ac/upload/pdf/rde-46-e47.pdf |
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| author | Clayton Tran Ellin Choi Brittany Watu Udochukwu Oyoyo Christopher Perry So Ran Kwon |
| author_facet | Clayton Tran Ellin Choi Brittany Watu Udochukwu Oyoyo Christopher Perry So Ran Kwon |
| author_sort | Clayton Tran |
| collection | DOAJ |
| description | ObjectivesThis study aimed to use a laboratory model to evaluate the efficacy of an experimental bleaching agent.Materials and MethodsThe model used human extracted molars that were treated and measured for bleaching efficacy. Teeth (n = 50) were distributed into 5 groups: Negative control (NC): immersion in water for 8 hours; Nanofibers (NFs): Experimental titanium dioxide nanofibers with stirring and light activation for 8 hours; Whitestrips (WS): Crest 3D White Glamorous White Whitestrips, 2 applications daily for 30 minutes, 14 days; 1% hydrogen peroxide (HP) standard: 1% hydrogen peroxide for 8 hours; and 30% HP standard: 30% hydrogen peroxide for 8 hours. Instrumental measurements were performed using a spectrophotometer. Results were recorded at baseline, 1-day post-bleaching, and 1-week post-bleaching. Kruskal-Wallis procedure was used to determine differences in color change. Pearson correlation was used to evaluate the relationship between visual and instrumental measurements. Tests of hypotheses were 2-sided with alpha = 0.05.ResultsThere was no significant difference in color parameters (L1, a1, b1, and shade guide units [SGU]) at baseline (p > 0.05). There was a significant difference among the groups for overall color change (ΔE*ab) and change in shade guide units (ΔSGU) at 1-day and 1-week post-bleaching (p < 0.05). The higher the HP concentration, the higher the color change as expressed in ΔSGU and ΔE*ab. The negative control exceeded the perceptibility threshold of ΔE* = 1.2 regardless of time point. NFs showed a decrease in chroma, but were not statistically different compared to the negative control.ConclusionsThe laboratory model was successful in screening an experimental bleaching agent. |
| format | Article |
| id | doaj-art-9ad11ccb938342468a3c3514b066c19d |
| institution | DOAJ |
| issn | 2234-7658 2234-7666 |
| language | English |
| publishDate | 2021-11-01 |
| publisher | Korean Academy of Conservative Dentistry |
| record_format | Article |
| series | Restorative Dentistry & Endodontics |
| spelling | doaj-art-9ad11ccb938342468a3c3514b066c19d2025-08-20T03:14:57ZengKorean Academy of Conservative DentistryRestorative Dentistry & Endodontics2234-76582234-76662021-11-01464e4710.5395/rde.2021.46.e47986Laboratory model to evaluate efficacy of an experimental titanium oxide nanofibers bleaching agentClayton Tran0Ellin Choi1Brittany Watu2Udochukwu Oyoyo3Christopher Perry4So Ran Kwon5Division of General Dentistry, Loma Linda University School of Dentistry, Loma Linda, California, USADivision of General Dentistry, Loma Linda University School of Dentistry, Loma Linda, California, USADivision of General Dentistry, Loma Linda University School of Dentistry, Loma Linda, California, USADivision of General Dentistry, Loma Linda University School of Dentistry, Loma Linda, California, USADepartment of Biochemistry, Loma Linda University School of Medicine, Loma Linda, California, USADivision of General Dentistry, Loma Linda University School of Dentistry, Loma Linda, California, USAObjectivesThis study aimed to use a laboratory model to evaluate the efficacy of an experimental bleaching agent.Materials and MethodsThe model used human extracted molars that were treated and measured for bleaching efficacy. Teeth (n = 50) were distributed into 5 groups: Negative control (NC): immersion in water for 8 hours; Nanofibers (NFs): Experimental titanium dioxide nanofibers with stirring and light activation for 8 hours; Whitestrips (WS): Crest 3D White Glamorous White Whitestrips, 2 applications daily for 30 minutes, 14 days; 1% hydrogen peroxide (HP) standard: 1% hydrogen peroxide for 8 hours; and 30% HP standard: 30% hydrogen peroxide for 8 hours. Instrumental measurements were performed using a spectrophotometer. Results were recorded at baseline, 1-day post-bleaching, and 1-week post-bleaching. Kruskal-Wallis procedure was used to determine differences in color change. Pearson correlation was used to evaluate the relationship between visual and instrumental measurements. Tests of hypotheses were 2-sided with alpha = 0.05.ResultsThere was no significant difference in color parameters (L1, a1, b1, and shade guide units [SGU]) at baseline (p > 0.05). There was a significant difference among the groups for overall color change (ΔE*ab) and change in shade guide units (ΔSGU) at 1-day and 1-week post-bleaching (p < 0.05). The higher the HP concentration, the higher the color change as expressed in ΔSGU and ΔE*ab. The negative control exceeded the perceptibility threshold of ΔE* = 1.2 regardless of time point. NFs showed a decrease in chroma, but were not statistically different compared to the negative control.ConclusionsThe laboratory model was successful in screening an experimental bleaching agent.http://rde.ac/upload/pdf/rde-46-e47.pdfcolorexperimental modeltitanium dioxidetooth bleaching |
| spellingShingle | Clayton Tran Ellin Choi Brittany Watu Udochukwu Oyoyo Christopher Perry So Ran Kwon Laboratory model to evaluate efficacy of an experimental titanium oxide nanofibers bleaching agent Restorative Dentistry & Endodontics color experimental model titanium dioxide tooth bleaching |
| title | Laboratory model to evaluate efficacy of an experimental titanium oxide nanofibers bleaching agent |
| title_full | Laboratory model to evaluate efficacy of an experimental titanium oxide nanofibers bleaching agent |
| title_fullStr | Laboratory model to evaluate efficacy of an experimental titanium oxide nanofibers bleaching agent |
| title_full_unstemmed | Laboratory model to evaluate efficacy of an experimental titanium oxide nanofibers bleaching agent |
| title_short | Laboratory model to evaluate efficacy of an experimental titanium oxide nanofibers bleaching agent |
| title_sort | laboratory model to evaluate efficacy of an experimental titanium oxide nanofibers bleaching agent |
| topic | color experimental model titanium dioxide tooth bleaching |
| url | http://rde.ac/upload/pdf/rde-46-e47.pdf |
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