Color-dependent defense mechanisms of Quinoa (Chenopodium quinoa Willd.) against Spodoptera exigua: metabolomic and transcriptomic insights

Abstract Background Quinoa (Chenopodium quinoa Willd.) exhibits a diverse and complex response to various organisms and environmental factors. The Spodoptera exigua elicits varying levels of damage in different crops. Secondary metabolites in quinoa induce defense mechanisms against S. exigua and pl...

Full description

Saved in:
Bibliographic Details
Main Authors: Junna Liu, Hanxue Li, Hongxin Wang, Ping Zhang, Qianchao Wang, Li Li, Heng Xie, Shunhe Cheng, Peng Qin
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Plant Biology
Subjects:
Online Access:https://doi.org/10.1186/s12870-025-06825-y
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849402654820663296
author Junna Liu
Hanxue Li
Hongxin Wang
Ping Zhang
Qianchao Wang
Li Li
Heng Xie
Shunhe Cheng
Peng Qin
author_facet Junna Liu
Hanxue Li
Hongxin Wang
Ping Zhang
Qianchao Wang
Li Li
Heng Xie
Shunhe Cheng
Peng Qin
author_sort Junna Liu
collection DOAJ
description Abstract Background Quinoa (Chenopodium quinoa Willd.) exhibits a diverse and complex response to various organisms and environmental factors. The Spodoptera exigua elicits varying levels of damage in different crops. Secondary metabolites in quinoa induce defense mechanisms against S. exigua and play a key role in influencing its feeding preferences. Although the co-evolution of quinoa and S. exigua has been explored, the understanding of the interaction between these species remains limited. We aimed to evaluate the defense mechanisms of differently colored quinoa (red, white, yellow, and black) against S. exigua using metabolomics and transcriptome analyses. Metabolomic analysis was used to identify insect-resistant metabolites in four differently colored quinoa cultivars, whereas transcriptome analysis was used to explore related pathways and gene associations. Results Quinoa resistant cultivars has higher levels of protective metabolites and mechanisms. Quinoa constitutive defense refers to the significant metabolism of ferulic compounds and lignin in plants to enhance their own resistance. Meanwhile, a significant expression of anthelmintic differential metabolites, including indole 3-acetic acid, choline, ferulic acid, caffeic acid, and anthranilic acid, was observed. The structural genes regulated by kaempferol (3,5,7,4′-tetrahydroxyflavone) and kaempferol-3-O-rhamnoside, along with genes downstream of quercetin-3-O-rhamnoside and MYB/MYB-related transcription factor, exhibited high expression levels in all four colors of insect-resistant quinoa. Among all quinoa cultivars, the red quinoa cultivar showed the most distinct variation in metabolite species and contents, insect-resistance was also relatively high. Conclusions These findings reveal that the types of different metabolites and MYB/MYB related transcription factors play a crucial role in influencing the expression of genes related to quinoa color and regulation, as well as in distinguishing the insect resistance of quinoa with different colors. These findings provide a basis for selecting and identifying new insect-resistant differently colored quinoa cultivars.
format Article
id doaj-art-9acf7f97c5e0465bb210ece3bbff19f8
institution Kabale University
issn 1471-2229
language English
publishDate 2025-07-01
publisher BMC
record_format Article
series BMC Plant Biology
spelling doaj-art-9acf7f97c5e0465bb210ece3bbff19f82025-08-20T03:37:29ZengBMCBMC Plant Biology1471-22292025-07-0125112510.1186/s12870-025-06825-yColor-dependent defense mechanisms of Quinoa (Chenopodium quinoa Willd.) against Spodoptera exigua: metabolomic and transcriptomic insightsJunna Liu0Hanxue Li1Hongxin Wang2Ping Zhang3Qianchao Wang4Li Li5Heng Xie6Shunhe Cheng7Peng Qin8College of Agronomy and Biotechnology, Yunnan Agricultural UniversityCollege of Agronomy and Biotechnology, Yunnan Agricultural UniversityCollege of Agronomy and Biotechnology, Yunnan Agricultural UniversityCollege of Agronomy and Biotechnology, Yunnan Agricultural UniversityCollege of Agronomy and Biotechnology, Yunnan Agricultural UniversityCollege of Agronomy and Biotechnology, Yunnan Agricultural UniversityCollege of Agronomy and Biotechnology, Yunnan Agricultural UniversityCollege of Agronomy and Biotechnology, Yunnan Agricultural UniversityCollege of Agronomy and Biotechnology, Yunnan Agricultural UniversityAbstract Background Quinoa (Chenopodium quinoa Willd.) exhibits a diverse and complex response to various organisms and environmental factors. The Spodoptera exigua elicits varying levels of damage in different crops. Secondary metabolites in quinoa induce defense mechanisms against S. exigua and play a key role in influencing its feeding preferences. Although the co-evolution of quinoa and S. exigua has been explored, the understanding of the interaction between these species remains limited. We aimed to evaluate the defense mechanisms of differently colored quinoa (red, white, yellow, and black) against S. exigua using metabolomics and transcriptome analyses. Metabolomic analysis was used to identify insect-resistant metabolites in four differently colored quinoa cultivars, whereas transcriptome analysis was used to explore related pathways and gene associations. Results Quinoa resistant cultivars has higher levels of protective metabolites and mechanisms. Quinoa constitutive defense refers to the significant metabolism of ferulic compounds and lignin in plants to enhance their own resistance. Meanwhile, a significant expression of anthelmintic differential metabolites, including indole 3-acetic acid, choline, ferulic acid, caffeic acid, and anthranilic acid, was observed. The structural genes regulated by kaempferol (3,5,7,4′-tetrahydroxyflavone) and kaempferol-3-O-rhamnoside, along with genes downstream of quercetin-3-O-rhamnoside and MYB/MYB-related transcription factor, exhibited high expression levels in all four colors of insect-resistant quinoa. Among all quinoa cultivars, the red quinoa cultivar showed the most distinct variation in metabolite species and contents, insect-resistance was also relatively high. Conclusions These findings reveal that the types of different metabolites and MYB/MYB related transcription factors play a crucial role in influencing the expression of genes related to quinoa color and regulation, as well as in distinguishing the insect resistance of quinoa with different colors. These findings provide a basis for selecting and identifying new insect-resistant differently colored quinoa cultivars.https://doi.org/10.1186/s12870-025-06825-yQuinoaMetabolomePlant defense responseSecondary metabolitesSpodoptera exiguaTranscriptome
spellingShingle Junna Liu
Hanxue Li
Hongxin Wang
Ping Zhang
Qianchao Wang
Li Li
Heng Xie
Shunhe Cheng
Peng Qin
Color-dependent defense mechanisms of Quinoa (Chenopodium quinoa Willd.) against Spodoptera exigua: metabolomic and transcriptomic insights
BMC Plant Biology
Quinoa
Metabolome
Plant defense response
Secondary metabolites
Spodoptera exigua
Transcriptome
title Color-dependent defense mechanisms of Quinoa (Chenopodium quinoa Willd.) against Spodoptera exigua: metabolomic and transcriptomic insights
title_full Color-dependent defense mechanisms of Quinoa (Chenopodium quinoa Willd.) against Spodoptera exigua: metabolomic and transcriptomic insights
title_fullStr Color-dependent defense mechanisms of Quinoa (Chenopodium quinoa Willd.) against Spodoptera exigua: metabolomic and transcriptomic insights
title_full_unstemmed Color-dependent defense mechanisms of Quinoa (Chenopodium quinoa Willd.) against Spodoptera exigua: metabolomic and transcriptomic insights
title_short Color-dependent defense mechanisms of Quinoa (Chenopodium quinoa Willd.) against Spodoptera exigua: metabolomic and transcriptomic insights
title_sort color dependent defense mechanisms of quinoa chenopodium quinoa willd against spodoptera exigua metabolomic and transcriptomic insights
topic Quinoa
Metabolome
Plant defense response
Secondary metabolites
Spodoptera exigua
Transcriptome
url https://doi.org/10.1186/s12870-025-06825-y
work_keys_str_mv AT junnaliu colordependentdefensemechanismsofquinoachenopodiumquinoawilldagainstspodopteraexiguametabolomicandtranscriptomicinsights
AT hanxueli colordependentdefensemechanismsofquinoachenopodiumquinoawilldagainstspodopteraexiguametabolomicandtranscriptomicinsights
AT hongxinwang colordependentdefensemechanismsofquinoachenopodiumquinoawilldagainstspodopteraexiguametabolomicandtranscriptomicinsights
AT pingzhang colordependentdefensemechanismsofquinoachenopodiumquinoawilldagainstspodopteraexiguametabolomicandtranscriptomicinsights
AT qianchaowang colordependentdefensemechanismsofquinoachenopodiumquinoawilldagainstspodopteraexiguametabolomicandtranscriptomicinsights
AT lili colordependentdefensemechanismsofquinoachenopodiumquinoawilldagainstspodopteraexiguametabolomicandtranscriptomicinsights
AT hengxie colordependentdefensemechanismsofquinoachenopodiumquinoawilldagainstspodopteraexiguametabolomicandtranscriptomicinsights
AT shunhecheng colordependentdefensemechanismsofquinoachenopodiumquinoawilldagainstspodopteraexiguametabolomicandtranscriptomicinsights
AT pengqin colordependentdefensemechanismsofquinoachenopodiumquinoawilldagainstspodopteraexiguametabolomicandtranscriptomicinsights