Lung Cancer and Interstitial Lung Diseases: A Systematic Review
Interstitial lung diseases (ILDs) represent a heterogeneous group of more than two hundred diseases of either known or unknown etiology with different pathogenesis and prognosis. Lung cancer, which is the major cause of cancer death in the developed countries, is mainly attributed to cigarette smoki...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Pulmonary Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/315918 |
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| _version_ | 1850170736544579584 |
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| author | Kostas Archontogeorgis Paschalis Steiropoulos Argyris Tzouvelekis Evangelia Nena Demosthenes Bouros |
| author_facet | Kostas Archontogeorgis Paschalis Steiropoulos Argyris Tzouvelekis Evangelia Nena Demosthenes Bouros |
| author_sort | Kostas Archontogeorgis |
| collection | DOAJ |
| description | Interstitial lung diseases (ILDs) represent a heterogeneous group of more than two hundred diseases of either known or unknown etiology with different pathogenesis and prognosis. Lung cancer, which is the major cause of cancer death in the developed countries, is mainly attributed to cigarette smoking and exposure to inhaled carcinogens. Different studies suggest a link between ILDs and lung cancer, through different pathogenetic mechanisms, such as inflammation, coagulation, dysregulated apoptosis, focal hypoxia, activation, and accumulation of myofibroblasts as well as extracellular matrix accumulation. This paper reviews current evidence on the association between lung cancer and interstitial lung diseases such as idiopathic pulmonary fibrosis, sarcoidosis, systemic sclerosis, dermatomyositis/polymyositis, rheumatoid arthritis, systemic lupus erythematosus, and pneumoconiosis. |
| format | Article |
| id | doaj-art-9acb299dd2f94025a63ffed80d105245 |
| institution | OA Journals |
| issn | 2090-1836 2090-1844 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pulmonary Medicine |
| spelling | doaj-art-9acb299dd2f94025a63ffed80d1052452025-08-20T02:20:25ZengWileyPulmonary Medicine2090-18362090-18442012-01-01201210.1155/2012/315918315918Lung Cancer and Interstitial Lung Diseases: A Systematic ReviewKostas Archontogeorgis0Paschalis Steiropoulos1Argyris Tzouvelekis2Evangelia Nena3Demosthenes Bouros4Department of Pneumonology, Medical School, Democritus University of Thrace, 68100 Alexandroupolis, GreeceDepartment of Pneumonology, Medical School, Democritus University of Thrace, 68100 Alexandroupolis, GreeceDepartment of Pneumonology, Medical School, Democritus University of Thrace, 68100 Alexandroupolis, GreeceLaboratory of Hygiene and Environmental Protection, Medical School, Democritus University of Thrace, 68100 Alexandroupolis, GreeceDepartment of Pneumonology, Medical School, Democritus University of Thrace, 68100 Alexandroupolis, GreeceInterstitial lung diseases (ILDs) represent a heterogeneous group of more than two hundred diseases of either known or unknown etiology with different pathogenesis and prognosis. Lung cancer, which is the major cause of cancer death in the developed countries, is mainly attributed to cigarette smoking and exposure to inhaled carcinogens. Different studies suggest a link between ILDs and lung cancer, through different pathogenetic mechanisms, such as inflammation, coagulation, dysregulated apoptosis, focal hypoxia, activation, and accumulation of myofibroblasts as well as extracellular matrix accumulation. This paper reviews current evidence on the association between lung cancer and interstitial lung diseases such as idiopathic pulmonary fibrosis, sarcoidosis, systemic sclerosis, dermatomyositis/polymyositis, rheumatoid arthritis, systemic lupus erythematosus, and pneumoconiosis.http://dx.doi.org/10.1155/2012/315918 |
| spellingShingle | Kostas Archontogeorgis Paschalis Steiropoulos Argyris Tzouvelekis Evangelia Nena Demosthenes Bouros Lung Cancer and Interstitial Lung Diseases: A Systematic Review Pulmonary Medicine |
| title | Lung Cancer and Interstitial Lung Diseases: A Systematic Review |
| title_full | Lung Cancer and Interstitial Lung Diseases: A Systematic Review |
| title_fullStr | Lung Cancer and Interstitial Lung Diseases: A Systematic Review |
| title_full_unstemmed | Lung Cancer and Interstitial Lung Diseases: A Systematic Review |
| title_short | Lung Cancer and Interstitial Lung Diseases: A Systematic Review |
| title_sort | lung cancer and interstitial lung diseases a systematic review |
| url | http://dx.doi.org/10.1155/2012/315918 |
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