Identification of seropositive cases of Chagas disease in pregnant women in a non-endemic risk area of the state of Mexico: The importance of screening prenatal

Objective: Our study aimed to identify seropositive cases of Trypanosoma cruzi in pregnant women from the northeastern region of the State of Mexico and underscore the importance of screening for this disease in prenatal care. Methods: We analyzed 879 serum samples from pregnant women in this non-en...

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Main Authors: Saúl González-Guzmán, José A. Crescencio-Trujillo, Carla I. Arroyo-Anduiza, María Guadalupe Córdova-Espinoza, Roberto Alvarado-Velázquez, Vladimir Paredes-Cervantes
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Parasite Epidemiology and Control
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Online Access:http://www.sciencedirect.com/science/article/pii/S2405673125000200
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author Saúl González-Guzmán
José A. Crescencio-Trujillo
Carla I. Arroyo-Anduiza
María Guadalupe Córdova-Espinoza
Roberto Alvarado-Velázquez
Vladimir Paredes-Cervantes
author_facet Saúl González-Guzmán
José A. Crescencio-Trujillo
Carla I. Arroyo-Anduiza
María Guadalupe Córdova-Espinoza
Roberto Alvarado-Velázquez
Vladimir Paredes-Cervantes
author_sort Saúl González-Guzmán
collection DOAJ
description Objective: Our study aimed to identify seropositive cases of Trypanosoma cruzi in pregnant women from the northeastern region of the State of Mexico and underscore the importance of screening for this disease in prenatal care. Methods: We analyzed 879 serum samples from pregnant women in this non-endemic area for antibodies to Trypanosoma cruzi. Results: We found a seroprevalence of 0.34 % to Trypanosoma cruzi in pregnant women aged 20 to 29. Conclusions: The confirmation of anti-Trypanosoma cruzi antibodies in 3 pregnant women in this non-endemic area further highlights the need to incorporate the diagnosis of this disease as part of prenatal care.
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issn 2405-6731
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publishDate 2025-05-01
publisher Elsevier
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series Parasite Epidemiology and Control
spelling doaj-art-9ac74935e2f6413e89b6d0579346b5292025-08-20T03:13:08ZengElsevierParasite Epidemiology and Control2405-67312025-05-0129e0042710.1016/j.parepi.2025.e00427Identification of seropositive cases of Chagas disease in pregnant women in a non-endemic risk area of the state of Mexico: The importance of screening prenatalSaúl González-Guzmán0José A. Crescencio-Trujillo1Carla I. Arroyo-Anduiza2María Guadalupe Córdova-Espinoza3Roberto Alvarado-Velázquez4Vladimir Paredes-Cervantes5Departamento de Investigación del Hospital Regional de Alta Especialidad de Zumpango, Estado de México, MexicoDepartamento de Investigación del Hospital Regional de Alta Especialidad de Zumpango, Estado de México, MexicoDepartamento de Investigación, Banco Central de Sangre del Centro Médico Nacional “La Raza”, IMSS, CDMX, MexicoLaboratorio de Inmunología, Escuela Militar de Graduados de Sanidad, SEDENA, Mexico; Laboratorio de Bacteriología Médica, Escuela Nacional de Ciencias Biológicas, IPN, MexicoDepartamento de Investigación del Hospital Regional de Alta Especialidad de Zumpango, Estado de México, MexicoLaboratorio Central, Biología Molecular, Hospital de Especialidades, Centro Médico Nacional ''La Raza'', Instituto Mexicano del Seguro Social (IMSS), CDMX, Mexico; Corresponding author at: Laboratorio Central, Biología Molecular, Hospital de Especialidades, Centro Médico Nacional ''La Raza'', Instituto Mexicano del Seguro Social (IMSS), Paseo de las Jacarandas S/N, Col. La Raza, Alc. Azcapotzalco, C.P. 02990 Ciudad de Mexico, CDMX, Mexico.Objective: Our study aimed to identify seropositive cases of Trypanosoma cruzi in pregnant women from the northeastern region of the State of Mexico and underscore the importance of screening for this disease in prenatal care. Methods: We analyzed 879 serum samples from pregnant women in this non-endemic area for antibodies to Trypanosoma cruzi. Results: We found a seroprevalence of 0.34 % to Trypanosoma cruzi in pregnant women aged 20 to 29. Conclusions: The confirmation of anti-Trypanosoma cruzi antibodies in 3 pregnant women in this non-endemic area further highlights the need to incorporate the diagnosis of this disease as part of prenatal care.http://www.sciencedirect.com/science/article/pii/S2405673125000200Congenital Chagas diseaseTrypanosoma cruziSeroprevalencePregnant womenMexico
spellingShingle Saúl González-Guzmán
José A. Crescencio-Trujillo
Carla I. Arroyo-Anduiza
María Guadalupe Córdova-Espinoza
Roberto Alvarado-Velázquez
Vladimir Paredes-Cervantes
Identification of seropositive cases of Chagas disease in pregnant women in a non-endemic risk area of the state of Mexico: The importance of screening prenatal
Parasite Epidemiology and Control
Congenital Chagas disease
Trypanosoma cruzi
Seroprevalence
Pregnant women
Mexico
title Identification of seropositive cases of Chagas disease in pregnant women in a non-endemic risk area of the state of Mexico: The importance of screening prenatal
title_full Identification of seropositive cases of Chagas disease in pregnant women in a non-endemic risk area of the state of Mexico: The importance of screening prenatal
title_fullStr Identification of seropositive cases of Chagas disease in pregnant women in a non-endemic risk area of the state of Mexico: The importance of screening prenatal
title_full_unstemmed Identification of seropositive cases of Chagas disease in pregnant women in a non-endemic risk area of the state of Mexico: The importance of screening prenatal
title_short Identification of seropositive cases of Chagas disease in pregnant women in a non-endemic risk area of the state of Mexico: The importance of screening prenatal
title_sort identification of seropositive cases of chagas disease in pregnant women in a non endemic risk area of the state of mexico the importance of screening prenatal
topic Congenital Chagas disease
Trypanosoma cruzi
Seroprevalence
Pregnant women
Mexico
url http://www.sciencedirect.com/science/article/pii/S2405673125000200
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