Metabolic reprogramming via mitochondrial delivery for enhanced maturation of chemically induced cardiomyocyte‐like cells

Metabolic reprogramming via mitochondrial delivery for enhanced maturation of chemically induced cardiomyocyte‐like cells

Abstract Heart degenerative diseases pose a significant challenge due to the limited ability of native heart to restore lost cardiomyocytes. Direct cellular reprogramming technology, particularly the use of small molecules, has emerged as a promising solution to prepare functional cardiomyocyte thro...

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Bibliographic Details
Main Authors: Yena Nam, Yoonji Song, Seung Ju Seo, Ga Ryang Ko, Seung Hyun Lee, Eunju Cha, Su Min Kwak, Sumin Kim, Mikyung Shin, Yoonhee Jin, Jung Seung Lee
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:MedComm
Subjects:
cardiomyocytes
cell reprogramming
metabolic regulation
mitochondrial transfer
Online Access:https://doi.org/10.1002/mco2.70005
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