HLA-DQA1*04:01 is related to a higher multiple sclerosis lesion load on T2/Flair MRI sequences

HLA-DQA1*04:01 is related to a higher multiple sclerosis lesion load on T2/Flair MRI sequences

ABSTRACT Background: The genetic predisposition to multiple sclerosis (MS) is associated with HLA alleles, especially HLA-DRB1*15:01. Objective: To identify associations between findings in magnetic resonance imaging (MRI) and genetic features in a Brazilian cohort of patients with MS. Methods: We r...

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Main Authors: Fabio NORO, Soniza Vieira ALVES-LEON, Fabricia Lima FONTES-DANTAS, Paulo Roberto VALLE BAHIA, Rodrigo Ferrone ANDREIUOLO, Fernanda Cristina RUEDA LOPES, Valeria Coelho Santa Rita PEREIRA, Livia de Almeida Afonso ABI-HAILA, Renan Amaral COUTINHO, Amanda Dutra de ARAUJO, Edson MARCHIORI
Format: Article
Language:English
Published: Thieme Revinter Publicações
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Multiple Sclerosis
HLA-DQ Antigens
HLA-DRB1 Chains
Genotype
Magnetic Resonance Imaging
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2021005026202&tlng=en
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