Airway microbiota associated D-phenylalanine promotes non-small cell lung cancer metastasis through epithelial mesenchymal transition

Airway microbiota associated D-phenylalanine promotes non-small cell lung cancer metastasis through epithelial mesenchymal transition

Abstract Background Lung cancer is the leading cause of cancer-related death worldwide, and patients with distant metastasis have a poor prognosis. Various studies have reported that microbiota and metabolites significantly differ between healthy individuals and lung cancer patients. However, the ef...

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Bibliographic Details
Main Authors: Lin Gao, Hua Liao, Yuehua Chen, Cuiping Ye, Liping Huang, Mingming Xu, Jiangzhou Du, Jinming Zhang, Danhui Huang, Shaoxi Cai, Hangming Dong
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Translational Medicine
Subjects:
Non-small cell lung cancer (NSCLC)
Airway metabolites
D-phenylalanine
Tumor metastasis
Epithelial mesenchymal transition (EMT)
Online Access:https://doi.org/10.1186/s12967-025-06701-1
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