The ACE2/Apelin Signaling, MicroRNAs, and Hypertension
The renin-angiotensin aldosterone system (RAAS) plays a pivotal role in the development of hypertension. Angiotensin converting enzyme 2 (ACE2), which primarily metabolises angiotensin (Ang) II to generate the beneficial heptapeptide Ang-(1-7), serves as a negative regulator of the RAAS. Apelin is a...
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Main Authors: | Lai-Jiang Chen, Ran Xu, Hui-Min Yu, Qing Chang, Jiu-Chang Zhong |
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Format: | Article |
Language: | English |
Published: |
Wiley
2015-01-01
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Series: | International Journal of Hypertension |
Online Access: | http://dx.doi.org/10.1155/2015/896861 |
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