Targeting AI-2 quorum sensing: harnessing natural products against Streptococcus suis biofilm infection

Targeting AI-2 quorum sensing: harnessing natural products against Streptococcus suis biofilm infection

Abstract The biofilm acts as a protective layer for Streptococcus suis (S. suis), contributing to the development of drug resistance and chronic infections. Autoinducer 2 (AI-2) quorum sensing represents the primary regulatory pathway governing biofilm formation in S. suis. Consequently, targeting A...

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Bibliographic Details
Main Authors: Shuji Gao, Shuo Yuan, Yingying Quan, Wenjie Jin, Yamin Shen, Rishun Li, Baobao Liu, Yuxin Wang, Li Yi, Shaohui Wang, Xiaogai Hou, Yang Wang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Veterinary Research
Subjects:
Streptococcus suis
biofilm
natural products
quorum sensing
virulence
Online Access:https://doi.org/10.1186/s13567-025-01450-x
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