Pediococcus pentosaceus JS35 improved flavor, metabolic profile of fermentation supernatant of mulberry leaf powder and increased its antioxidant capacity

Pediococcus pentosaceus JS35 was used to improve flavor, metabolic profile and antioxidant activity of mulberry leaf powder. Gas chromatography ion mobility spectrometry (GC-IMS) analysis revealed that fermentation increased the contents of floral and fruity flavor compounds such as dihydrolinalool...

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Main Authors: Caiyan Meng, Yutong Wang, Jiawen Xie, Jiajia Xuan, Jingze Geng, Guanhui Liu, Jie Tu, Hang Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Nutrition
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Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2025.1551689/full
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author Caiyan Meng
Yutong Wang
Jiawen Xie
Jiajia Xuan
Jingze Geng
Guanhui Liu
Guanhui Liu
Jie Tu
Hang Xiao
author_facet Caiyan Meng
Yutong Wang
Jiawen Xie
Jiajia Xuan
Jingze Geng
Guanhui Liu
Guanhui Liu
Jie Tu
Hang Xiao
author_sort Caiyan Meng
collection DOAJ
description Pediococcus pentosaceus JS35 was used to improve flavor, metabolic profile and antioxidant activity of mulberry leaf powder. Gas chromatography ion mobility spectrometry (GC-IMS) analysis revealed that fermentation increased the contents of floral and fruity flavor compounds such as dihydrolinalool and 2-phenylethanol, while decreased the grassy, pungent odor compounds. Non-targeted metabolomics analysis showed that Pediococcus pentosaceus JS35 altered the metabolic profile of mulberry leaf, especially increased the content of flavonoids metabolites such as kaempferol, quercetin and daidzein. Compared with the unfermented sample, the fermented supernatant had higher antioxidant capacity in vitro and in Caenorhabditis elegans. Furthermore, the fermented supernatant supplementation significantly prolonged the lifespan of Caenorhabditis elegans. In conclusion, fermentation by Pediococcus pentosaceus JS35 improved the flavor and active compounds of mulberry leaf, and the fermented product had effective antioxidant capacity. This study will provide ideas for the application of Pediococcus pentosaceus JS35 and the processing of mulberry leaf into functional foods or food ingredient.
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language English
publishDate 2025-03-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Nutrition
spelling doaj-art-9ab8ddd12d934b449c4c434ef143e29f2025-08-20T03:00:59ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2025-03-011210.3389/fnut.2025.15516891551689Pediococcus pentosaceus JS35 improved flavor, metabolic profile of fermentation supernatant of mulberry leaf powder and increased its antioxidant capacityCaiyan Meng0Yutong Wang1Jiawen Xie2Jiajia Xuan3Jingze Geng4Guanhui Liu5Guanhui Liu6Jie Tu7Hang Xiao8College of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, ChinaCollege of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, ChinaCollege of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, ChinaCollege of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, ChinaCollege of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, ChinaCollege of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, ChinaSchool of Grain Science and Technology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, ChinaCollege of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, ChinaDepartment of Food Science, University of Massachusetts, Amherst, MA, United StatesPediococcus pentosaceus JS35 was used to improve flavor, metabolic profile and antioxidant activity of mulberry leaf powder. Gas chromatography ion mobility spectrometry (GC-IMS) analysis revealed that fermentation increased the contents of floral and fruity flavor compounds such as dihydrolinalool and 2-phenylethanol, while decreased the grassy, pungent odor compounds. Non-targeted metabolomics analysis showed that Pediococcus pentosaceus JS35 altered the metabolic profile of mulberry leaf, especially increased the content of flavonoids metabolites such as kaempferol, quercetin and daidzein. Compared with the unfermented sample, the fermented supernatant had higher antioxidant capacity in vitro and in Caenorhabditis elegans. Furthermore, the fermented supernatant supplementation significantly prolonged the lifespan of Caenorhabditis elegans. In conclusion, fermentation by Pediococcus pentosaceus JS35 improved the flavor and active compounds of mulberry leaf, and the fermented product had effective antioxidant capacity. This study will provide ideas for the application of Pediococcus pentosaceus JS35 and the processing of mulberry leaf into functional foods or food ingredient.https://www.frontiersin.org/articles/10.3389/fnut.2025.1551689/fullPediococcus pentosaceusmulberry leafflavormetabolic profilesantioxidant capacity
spellingShingle Caiyan Meng
Yutong Wang
Jiawen Xie
Jiajia Xuan
Jingze Geng
Guanhui Liu
Guanhui Liu
Jie Tu
Hang Xiao
Pediococcus pentosaceus JS35 improved flavor, metabolic profile of fermentation supernatant of mulberry leaf powder and increased its antioxidant capacity
Frontiers in Nutrition
Pediococcus pentosaceus
mulberry leaf
flavor
metabolic profiles
antioxidant capacity
title Pediococcus pentosaceus JS35 improved flavor, metabolic profile of fermentation supernatant of mulberry leaf powder and increased its antioxidant capacity
title_full Pediococcus pentosaceus JS35 improved flavor, metabolic profile of fermentation supernatant of mulberry leaf powder and increased its antioxidant capacity
title_fullStr Pediococcus pentosaceus JS35 improved flavor, metabolic profile of fermentation supernatant of mulberry leaf powder and increased its antioxidant capacity
title_full_unstemmed Pediococcus pentosaceus JS35 improved flavor, metabolic profile of fermentation supernatant of mulberry leaf powder and increased its antioxidant capacity
title_short Pediococcus pentosaceus JS35 improved flavor, metabolic profile of fermentation supernatant of mulberry leaf powder and increased its antioxidant capacity
title_sort pediococcus pentosaceus js35 improved flavor metabolic profile of fermentation supernatant of mulberry leaf powder and increased its antioxidant capacity
topic Pediococcus pentosaceus
mulberry leaf
flavor
metabolic profiles
antioxidant capacity
url https://www.frontiersin.org/articles/10.3389/fnut.2025.1551689/full
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