Real world data on digital remote refraction in a healthy population of 14,680 eyes
Abstract Refractive errors are the leading cause of preventable visual impairment, to which web-based remote refraction could contribute. We report real-world 2021–2022 data of the underlying algorithm and validated these to conventional prescriptions among healthy individuals (high visual acuity an...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-02-01
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| Series: | npj Digital Medicine |
| Online Access: | https://doi.org/10.1038/s41746-025-01453-0 |
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| _version_ | 1823861578959683584 |
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| author | Casper van der Zee Heshow Jamal Marc Muijzer Laurence Frank Gerko Vink Robert Wisse |
| author_facet | Casper van der Zee Heshow Jamal Marc Muijzer Laurence Frank Gerko Vink Robert Wisse |
| author_sort | Casper van der Zee |
| collection | DOAJ |
| description | Abstract Refractive errors are the leading cause of preventable visual impairment, to which web-based remote refraction could contribute. We report real-world 2021–2022 data of the underlying algorithm and validated these to conventional prescriptions among healthy individuals (high visual acuity and satisfactied current refraction). Participants were 18–45 years with a spherical (S) error between −3.50 + 2.00S to −2.00 Diopter Cylinder (DC), reported as Spherical Equivalent (SEQ) in mean differences and 95% Limits of agreement. Consecutive measurements (n = 14,680) were assessed of which n = 6386 selected for validation. The mean difference was 0.01D(SD 0.69) and −0.73D(SD 0.92) for myopes and hyperopes respectively. This algorithm shows variation, nonetheless, 67% and 82% of myopes were within ±0.5 and ±0.75D. The test underestimates hyperopes (34% and 50% within ±0.5D and ±0.75D) and had inconsistencies distinguishing hyperopia. This proof-of-concept shows home testing has the potency to increase accessibility to care by delivering a valuable alternative for uncomplicated refractive assessments. |
| format | Article |
| id | doaj-art-9ab85141e48a4114acdca48bb97be9d2 |
| institution | Kabale University |
| issn | 2398-6352 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | npj Digital Medicine |
| spelling | doaj-art-9ab85141e48a4114acdca48bb97be9d22025-02-09T12:55:39ZengNature Portfolionpj Digital Medicine2398-63522025-02-01811910.1038/s41746-025-01453-0Real world data on digital remote refraction in a healthy population of 14,680 eyesCasper van der Zee0Heshow Jamal1Marc Muijzer2Laurence Frank3Gerko Vink4Robert Wisse5Ophthalmology Department, University Medical Center UtrechtEasee B.V.Easee B.V.Department of Methodology and Statistics, Faculty of Social and Behavioural Sciences, Utrecht UniversityDepartment of Methodology and Statistics, Faculty of Social and Behavioural Sciences, Utrecht UniversityOphthalmology Department, University Medical Center UtrechtAbstract Refractive errors are the leading cause of preventable visual impairment, to which web-based remote refraction could contribute. We report real-world 2021–2022 data of the underlying algorithm and validated these to conventional prescriptions among healthy individuals (high visual acuity and satisfactied current refraction). Participants were 18–45 years with a spherical (S) error between −3.50 + 2.00S to −2.00 Diopter Cylinder (DC), reported as Spherical Equivalent (SEQ) in mean differences and 95% Limits of agreement. Consecutive measurements (n = 14,680) were assessed of which n = 6386 selected for validation. The mean difference was 0.01D(SD 0.69) and −0.73D(SD 0.92) for myopes and hyperopes respectively. This algorithm shows variation, nonetheless, 67% and 82% of myopes were within ±0.5 and ±0.75D. The test underestimates hyperopes (34% and 50% within ±0.5D and ±0.75D) and had inconsistencies distinguishing hyperopia. This proof-of-concept shows home testing has the potency to increase accessibility to care by delivering a valuable alternative for uncomplicated refractive assessments.https://doi.org/10.1038/s41746-025-01453-0 |
| spellingShingle | Casper van der Zee Heshow Jamal Marc Muijzer Laurence Frank Gerko Vink Robert Wisse Real world data on digital remote refraction in a healthy population of 14,680 eyes npj Digital Medicine |
| title | Real world data on digital remote refraction in a healthy population of 14,680 eyes |
| title_full | Real world data on digital remote refraction in a healthy population of 14,680 eyes |
| title_fullStr | Real world data on digital remote refraction in a healthy population of 14,680 eyes |
| title_full_unstemmed | Real world data on digital remote refraction in a healthy population of 14,680 eyes |
| title_short | Real world data on digital remote refraction in a healthy population of 14,680 eyes |
| title_sort | real world data on digital remote refraction in a healthy population of 14 680 eyes |
| url | https://doi.org/10.1038/s41746-025-01453-0 |
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