Dishevelled-1 regulates global transcriptomic changes and associates with ETS1 transcription factor
Abstract Dishevelled (DVL) is a crucial component of the Wnt-signaling pathway and is vital for multiple physiological processes. Previously thought to have a classically cytoplasmic role, the discovery of DVL nuclear translocation reframed how it is viewed functionally. Although significant progres...
Saved in:
| Main Authors: | Dalia Martinez-Marin, Monica Sharma, Jenna C. van Wunnik, Flávia Sardela de Miranda, Geetha Priya Boligala, Ella C. Jull, Grace C. Stroman, Rachel L. Babcock, Kevin Pruitt |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-61551-1 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Frizzled receptors: gatekeepers of Wnt signaling in development and disease
by: Dalia Martinez-Marin, et al.
Published: (2025-05-01) -
Structural and Functional Insights into Dishevelled-Mediated Wnt Signaling
by: Lei Wang, et al.
Published: (2024-11-01) -
Dishevelled localization and function are differentially regulated by structurally distinct sterols
by: Sonali Sengupta, et al.
Published: (2025-06-01) -
Dact1 induces Dishevelled oligomerization to facilitate binding partner switch and signalosome formation during convergent extension
by: Allyson Angermeier, et al.
Published: (2025-03-01) -
The nanoscale organization of the Wnt signaling integrator Dishevelled in the vegetal cortex domain of an egg and early embryo.
by: John H Henson, et al.
Published: (2021-01-01)