Culture-Negative Peritonitis and the Latest Diagnostic Techniques

Background: Peritonitis is a common and serious complication of peritoneal dialysis that results in considerable morbidity, mortality, and increased healthcare costs. A positive culture-based microorganism test is one of the main criteria for the diagnosis of peritonitis. However, the rat...

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Main Authors: Jiajia Ye, Jing Sun, Dan Chen, Huanhuan Cao, Yi Lv, Chen Ye, Yumei Wang, Huajun Jiang
Format: Article
Language:English
Published: Karger Publishers 2025-01-01
Series:Kidney Diseases
Online Access:https://karger.com/article/doi/10.1159/000542870
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author Jiajia Ye
Jing Sun
Dan Chen
Huanhuan Cao
Yi Lv
Chen Ye
Yumei Wang
Huajun Jiang
author_facet Jiajia Ye
Jing Sun
Dan Chen
Huanhuan Cao
Yi Lv
Chen Ye
Yumei Wang
Huajun Jiang
author_sort Jiajia Ye
collection DOAJ
description Background: Peritonitis is a common and serious complication of peritoneal dialysis that results in considerable morbidity, mortality, and increased healthcare costs. A positive culture-based microorganism test is one of the main criteria for the diagnosis of peritonitis. However, the rates of positive bacterial culture remain quite low. Summary: Peritonitis is a frequently encountered and consequential complication of peritoneal dialysis that poses a significant clinical burden in terms of morbidity, mortality, and healthcare expenditure. The reliance on culture-positive microbiological tests as a cornerstone of peritonitis diagnosis often results in a relatively low rate of positive results. Key Messages: This article aimed to present a comprehensive synthesis and critical analysis of the most recent diagnostic modalities used to identify peritonitis-associated pathogens in peritoneal dialysis. Emphasis was placed on both direct diagnostic tools for pathogen identification and rapid detection methodologies that facilitate expedited pathogen diagnosis in peritonitis.
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issn 2296-9357
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publishDate 2025-01-01
publisher Karger Publishers
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series Kidney Diseases
spelling doaj-art-9aaee6a07cc240708f0382737d8ae4d12025-08-20T02:31:55ZengKarger PublishersKidney Diseases2296-93572025-01-01111253710.1159/000542870Culture-Negative Peritonitis and the Latest Diagnostic TechniquesJiajia YeJing SunDan ChenHuanhuan CaoYi LvChen YeYumei WangHuajun Jiang Background: Peritonitis is a common and serious complication of peritoneal dialysis that results in considerable morbidity, mortality, and increased healthcare costs. A positive culture-based microorganism test is one of the main criteria for the diagnosis of peritonitis. However, the rates of positive bacterial culture remain quite low. Summary: Peritonitis is a frequently encountered and consequential complication of peritoneal dialysis that poses a significant clinical burden in terms of morbidity, mortality, and healthcare expenditure. The reliance on culture-positive microbiological tests as a cornerstone of peritonitis diagnosis often results in a relatively low rate of positive results. Key Messages: This article aimed to present a comprehensive synthesis and critical analysis of the most recent diagnostic modalities used to identify peritonitis-associated pathogens in peritoneal dialysis. Emphasis was placed on both direct diagnostic tools for pathogen identification and rapid detection methodologies that facilitate expedited pathogen diagnosis in peritonitis. https://karger.com/article/doi/10.1159/000542870
spellingShingle Jiajia Ye
Jing Sun
Dan Chen
Huanhuan Cao
Yi Lv
Chen Ye
Yumei Wang
Huajun Jiang
Culture-Negative Peritonitis and the Latest Diagnostic Techniques
Kidney Diseases
title Culture-Negative Peritonitis and the Latest Diagnostic Techniques
title_full Culture-Negative Peritonitis and the Latest Diagnostic Techniques
title_fullStr Culture-Negative Peritonitis and the Latest Diagnostic Techniques
title_full_unstemmed Culture-Negative Peritonitis and the Latest Diagnostic Techniques
title_short Culture-Negative Peritonitis and the Latest Diagnostic Techniques
title_sort culture negative peritonitis and the latest diagnostic techniques
url https://karger.com/article/doi/10.1159/000542870
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AT jingsun culturenegativeperitonitisandthelatestdiagnostictechniques
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AT huanhuancao culturenegativeperitonitisandthelatestdiagnostictechniques
AT yilv culturenegativeperitonitisandthelatestdiagnostictechniques
AT chenye culturenegativeperitonitisandthelatestdiagnostictechniques
AT yumeiwang culturenegativeperitonitisandthelatestdiagnostictechniques
AT huajunjiang culturenegativeperitonitisandthelatestdiagnostictechniques