A Case of Haemophilus haemolyticus Meningitis

Haemophilus haemolyticus is a gram-negative bacillus respiratory tract commensal with reduced capacity to invade mucosal epithelia. Nontypeable (that is, nonencapsulated) Haemophilus influenzae and H haemolyticus are difficult to differentiate from each other but, due to advancements in genotype ass...

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Main Authors: Jane Qu, Sunil R. Ramaswamy, Rodolfo M. Alpizar-Rivas
Format: Article
Language:English
Published: American College of Physicians 2024-11-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2023.0473
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author Jane Qu
Sunil R. Ramaswamy
Rodolfo M. Alpizar-Rivas
author_facet Jane Qu
Sunil R. Ramaswamy
Rodolfo M. Alpizar-Rivas
author_sort Jane Qu
collection DOAJ
description Haemophilus haemolyticus is a gram-negative bacillus respiratory tract commensal with reduced capacity to invade mucosal epithelia. Nontypeable (that is, nonencapsulated) Haemophilus influenzae and H haemolyticus are difficult to differentiate from each other but, due to advancements in genotype assays, H haemolyticus has been found to cause invasive disease. We describe a rare case of H haemolyticus bacteremia and meningitis in a 50-year-old man who presented with altered sensorium. He was found to have a low IgM level, leading to speculation that a decreased immune system contributed to his presentation. However, he ultimately declined further immunosuppressive work-up.
format Article
id doaj-art-9a948d7d40ee47fda1d2d437fb063aeb
institution OA Journals
issn 2767-7664
language English
publishDate 2024-11-01
publisher American College of Physicians
record_format Article
series Annals of Internal Medicine: Clinical Cases
spelling doaj-art-9a948d7d40ee47fda1d2d437fb063aeb2025-08-20T02:11:43ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642024-11-0131110.7326/aimcc.2023.0473A Case of Haemophilus haemolyticus MeningitisJane Qu0Sunil R. Ramaswamy1Rodolfo M. Alpizar-Rivas21University of Rochester Medical Center, Department of Medicine, Rochester, New York2University of California, Riverside, Department of Medicine, Riverside, California1University of Rochester Medical Center, Department of Medicine, Rochester, New YorkHaemophilus haemolyticus is a gram-negative bacillus respiratory tract commensal with reduced capacity to invade mucosal epithelia. Nontypeable (that is, nonencapsulated) Haemophilus influenzae and H haemolyticus are difficult to differentiate from each other but, due to advancements in genotype assays, H haemolyticus has been found to cause invasive disease. We describe a rare case of H haemolyticus bacteremia and meningitis in a 50-year-old man who presented with altered sensorium. He was found to have a low IgM level, leading to speculation that a decreased immune system contributed to his presentation. However, he ultimately declined further immunosuppressive work-up.https://www.acpjournals.org/doi/10.7326/aimcc.2023.0473
spellingShingle Jane Qu
Sunil R. Ramaswamy
Rodolfo M. Alpizar-Rivas
A Case of Haemophilus haemolyticus Meningitis
Annals of Internal Medicine: Clinical Cases
title A Case of Haemophilus haemolyticus Meningitis
title_full A Case of Haemophilus haemolyticus Meningitis
title_fullStr A Case of Haemophilus haemolyticus Meningitis
title_full_unstemmed A Case of Haemophilus haemolyticus Meningitis
title_short A Case of Haemophilus haemolyticus Meningitis
title_sort case of haemophilus haemolyticus meningitis
url https://www.acpjournals.org/doi/10.7326/aimcc.2023.0473
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AT sunilrramaswamy caseofhaemophilushaemolyticusmeningitis
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