Obesity and Gastrointestinal Diseases

The prevalence of obesity in the Japanese population has been increasing dramatically in step with the Westernization of lifestyles and food ways. Our study demonstrated significant associations between obesity and a number of gastrointestinal disorders in a large sample population in Japan. We demo...

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Main Authors: Ai Fujimoto, Shu Hoteya, Toshiro Iizuka, Osamu Ogawa, Toshifumi Mitani, Yuichiro Kuroki, Akira Matsui, Masanori Nakamura, Daisuke Kikuchi, Satoshi Yamashita, Tsukasa Furuhata, Akihiro Yamada, Noriko Nishida, Koji Arase, Mitsuyo Hashimoto, Yoshinori Igarashi, Mitsuru Kaise
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2013/760574
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author Ai Fujimoto
Shu Hoteya
Toshiro Iizuka
Osamu Ogawa
Toshifumi Mitani
Yuichiro Kuroki
Akira Matsui
Masanori Nakamura
Daisuke Kikuchi
Satoshi Yamashita
Tsukasa Furuhata
Akihiro Yamada
Noriko Nishida
Koji Arase
Mitsuyo Hashimoto
Yoshinori Igarashi
Mitsuru Kaise
author_facet Ai Fujimoto
Shu Hoteya
Toshiro Iizuka
Osamu Ogawa
Toshifumi Mitani
Yuichiro Kuroki
Akira Matsui
Masanori Nakamura
Daisuke Kikuchi
Satoshi Yamashita
Tsukasa Furuhata
Akihiro Yamada
Noriko Nishida
Koji Arase
Mitsuyo Hashimoto
Yoshinori Igarashi
Mitsuru Kaise
author_sort Ai Fujimoto
collection DOAJ
description The prevalence of obesity in the Japanese population has been increasing dramatically in step with the Westernization of lifestyles and food ways. Our study demonstrated significant associations between obesity and a number of gastrointestinal disorders in a large sample population in Japan. We demonstrated that reflux esophagitis and hiatal hernia were strongly related to obesity (BMI > 25) in the Japanese. In particular, obesity with young male was a high risk for these diseases. On the other hand, it has been reported that obesity is also associated with Barrett’s esophagus and colorectal adenoma; however, obesity was not a risk factor for these diseases in our study. The difference of ethnicity of our subjects may partly explain why we found no data to implicate obesity as a risk factor for Barrett’s esophagus. Arterial sclerosis associated with advanced age and hyperglycemia was accompanied by an increased risk of colorectal adenoma.
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language English
publishDate 2013-01-01
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series Gastroenterology Research and Practice
spelling doaj-art-9a7e6bc0c9fb4a69a902261a4e4114dd2025-02-03T05:53:44ZengWileyGastroenterology Research and Practice1687-61211687-630X2013-01-01201310.1155/2013/760574760574Obesity and Gastrointestinal DiseasesAi Fujimoto0Shu Hoteya1Toshiro Iizuka2Osamu Ogawa3Toshifumi Mitani4Yuichiro Kuroki5Akira Matsui6Masanori Nakamura7Daisuke Kikuchi8Satoshi Yamashita9Tsukasa Furuhata10Akihiro Yamada11Noriko Nishida12Koji Arase13Mitsuyo Hashimoto14Yoshinori Igarashi15Mitsuru Kaise16Department of Gastroenterology, Toranomon Hospital, 2-2-2, Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2, Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2, Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2, Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2, Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2, Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2, Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2, Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2, Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2, Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2, Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2, Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2, Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2, Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2, Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology and Hepatology, Toho University, Omori Medical Center, 6-11-1 Omorinishi, Otaku, Tokyo 143-8541, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2, Toranomon, Minato-ku, Tokyo 105-8470, JapanThe prevalence of obesity in the Japanese population has been increasing dramatically in step with the Westernization of lifestyles and food ways. Our study demonstrated significant associations between obesity and a number of gastrointestinal disorders in a large sample population in Japan. We demonstrated that reflux esophagitis and hiatal hernia were strongly related to obesity (BMI > 25) in the Japanese. In particular, obesity with young male was a high risk for these diseases. On the other hand, it has been reported that obesity is also associated with Barrett’s esophagus and colorectal adenoma; however, obesity was not a risk factor for these diseases in our study. The difference of ethnicity of our subjects may partly explain why we found no data to implicate obesity as a risk factor for Barrett’s esophagus. Arterial sclerosis associated with advanced age and hyperglycemia was accompanied by an increased risk of colorectal adenoma.http://dx.doi.org/10.1155/2013/760574
spellingShingle Ai Fujimoto
Shu Hoteya
Toshiro Iizuka
Osamu Ogawa
Toshifumi Mitani
Yuichiro Kuroki
Akira Matsui
Masanori Nakamura
Daisuke Kikuchi
Satoshi Yamashita
Tsukasa Furuhata
Akihiro Yamada
Noriko Nishida
Koji Arase
Mitsuyo Hashimoto
Yoshinori Igarashi
Mitsuru Kaise
Obesity and Gastrointestinal Diseases
Gastroenterology Research and Practice
title Obesity and Gastrointestinal Diseases
title_full Obesity and Gastrointestinal Diseases
title_fullStr Obesity and Gastrointestinal Diseases
title_full_unstemmed Obesity and Gastrointestinal Diseases
title_short Obesity and Gastrointestinal Diseases
title_sort obesity and gastrointestinal diseases
url http://dx.doi.org/10.1155/2013/760574
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