Pregnancy and contraceptive use among participants of childbearing potential in the HVTN 705 HIV vaccine trial in Southern Africa

Pregnancy and contraceptive use among participants of childbearing potential in the HVTN 705 HIV vaccine trial in Southern Africa

BackgroundHIV vaccine trial participants include sexually active cisgender females who agree to avoid pregnancy during the active vaccination period. Nevertheless, some pregnancies occur in almost all studies. We examined contraceptive use, pregnancy incidence, and the relationship between pregnancy...

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Main Authors: Pamela Mda, Kathryn Mngadi, Bo Zhang, Randy Burnham, Michal Juraska, Ollivier Hyrien, Nigel Garrett, Thozama Dubula, Sinalo Toni, Sibi Joseph, Phillip Kotze, Susan Buchbinder, Azwidihwi Takalani, Frank Tomaka, Alexander Luedtke, Wouter Willems, Edith Swann, Julia Hutter, Huub Gelderblom, M. Juliana McElrath, Ludo Lavreys, Lynda Stranix-Chibanda, Alison C. Roxby, Linda-Gail Bekker, Glenda E. Gray
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Reproductive Health
Subjects:
HIV-1 vaccine trials
HIV prevention
HIV incidence
contraception
pregnancy
Online Access:https://www.frontiersin.org/articles/10.3389/frph.2025.1565933/full
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