Creation and validation of a new index to predict pneumonia associated with ischemic stroke
<p><strong>Background</strong>: pneumonia associated with ischemic stroke is the medical complication with the greatest impact in this group of patients, as it increases the risk of recurrence, decreases functional recovery and triples the number of deaths.<br /><strong>...
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Centro Provincial de Información de Ciencias Médicas. Cienfuegos
2022-12-01
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| Series: | Medisur |
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| Online Access: | http://medisur.sld.cu/index.php/medisur/article/view/5477 |
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| author | Alexis Suárez Quesada Alexis Álvarez Aliaga Andrés José Quesada Vázquez |
| author_facet | Alexis Suárez Quesada Alexis Álvarez Aliaga Andrés José Quesada Vázquez |
| author_sort | Alexis Suárez Quesada |
| collection | DOAJ |
| description | <p><strong>Background</strong>: pneumonia associated with ischemic stroke is the medical complication with the greatest impact in this group of patients, as it increases the risk of recurrence, decreases functional recovery and triples the number of deaths.<br /><strong>Objective</strong>: to create and validate a new predictive index of pneumonia associated with ischemic stroke.<br /><strong>Methods</strong>: 725 patients with a diagnosis of ischemic stroke, belonging to a prospective cohort, treated at the Carlos Manuel de Céspedes Provincial General Hospital in Bayamo, Granma province, were studied. The sample was randomly divided into a construction cohort with 509 patients for the creation of the index, and another validation cohort with 216 patients. A new quantitative index of four risk categories was obtained from the corresponding regression coefficients of each independent predictor.<br /><strong>Results</strong>: the variables that contributed the highest score to the index were dysphagia (28), the NIHSS scale ≥ 12 points (24) and heart failure (22). The new index presented good discriminative capacity (area under the ROC curve = 0.94). In the validation sample, it showed better discrimination capacity, greater validity and reliability when compared with the international A2DS2 and ISAN indices.<strong><br />Conclusion</strong>: the new index created and validated allows to satisfactorily predict the development of pneumonia associated with ischemic stroke. It is a useful and safe tool for use in healthcare practice.</p> |
| format | Article |
| id | doaj-art-9a793b69b9b54c23b2922335d8d9dbfa |
| institution | Kabale University |
| issn | 1727-897X |
| language | Spanish |
| publishDate | 2022-12-01 |
| publisher | Centro Provincial de Información de Ciencias Médicas. Cienfuegos |
| record_format | Article |
| series | Medisur |
| spelling | doaj-art-9a793b69b9b54c23b2922335d8d9dbfa2025-01-30T21:28:59ZspaCentro Provincial de Información de Ciencias Médicas. CienfuegosMedisur1727-897X2022-12-01206104010522202Creation and validation of a new index to predict pneumonia associated with ischemic strokeAlexis Suárez Quesada0Alexis Álvarez Aliaga1Andrés José Quesada Vázquez2Hospital General Provincial Carlos Manuel de Céspedes. Bayamo, GranmaHospital General Provincial Carlos Manuel de Céspedes. Bayamo, GranmaHospital General Provincial Carlos Manuel de Céspedes. Bayamo, Granma<p><strong>Background</strong>: pneumonia associated with ischemic stroke is the medical complication with the greatest impact in this group of patients, as it increases the risk of recurrence, decreases functional recovery and triples the number of deaths.<br /><strong>Objective</strong>: to create and validate a new predictive index of pneumonia associated with ischemic stroke.<br /><strong>Methods</strong>: 725 patients with a diagnosis of ischemic stroke, belonging to a prospective cohort, treated at the Carlos Manuel de Céspedes Provincial General Hospital in Bayamo, Granma province, were studied. The sample was randomly divided into a construction cohort with 509 patients for the creation of the index, and another validation cohort with 216 patients. A new quantitative index of four risk categories was obtained from the corresponding regression coefficients of each independent predictor.<br /><strong>Results</strong>: the variables that contributed the highest score to the index were dysphagia (28), the NIHSS scale ≥ 12 points (24) and heart failure (22). The new index presented good discriminative capacity (area under the ROC curve = 0.94). In the validation sample, it showed better discrimination capacity, greater validity and reliability when compared with the international A2DS2 and ISAN indices.<strong><br />Conclusion</strong>: the new index created and validated allows to satisfactorily predict the development of pneumonia associated with ischemic stroke. It is a useful and safe tool for use in healthcare practice.</p>http://medisur.sld.cu/index.php/medisur/article/view/5477accidente cerebrovascularneumoníafactores de riesgoestudios de cohorteinfección hospitalaria |
| spellingShingle | Alexis Suárez Quesada Alexis Álvarez Aliaga Andrés José Quesada Vázquez Creation and validation of a new index to predict pneumonia associated with ischemic stroke Medisur accidente cerebrovascular neumonía factores de riesgo estudios de cohorte infección hospitalaria |
| title | Creation and validation of a new index to predict pneumonia associated with ischemic stroke |
| title_full | Creation and validation of a new index to predict pneumonia associated with ischemic stroke |
| title_fullStr | Creation and validation of a new index to predict pneumonia associated with ischemic stroke |
| title_full_unstemmed | Creation and validation of a new index to predict pneumonia associated with ischemic stroke |
| title_short | Creation and validation of a new index to predict pneumonia associated with ischemic stroke |
| title_sort | creation and validation of a new index to predict pneumonia associated with ischemic stroke |
| topic | accidente cerebrovascular neumonía factores de riesgo estudios de cohorte infección hospitalaria |
| url | http://medisur.sld.cu/index.php/medisur/article/view/5477 |
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