Epidemiology of urinary tract infections in the Middle East and North Africa, 1990–2021
Abstract Objective This research reports the incidence, mortality, and disability-adjusted life years (DALYs) associated with urinary tract infections (UTIs) in the Middle East and North Africa (MENA) region, stratified by sex, age, and Socio-demographic Index (SDI) from 1990 to 2021. Methods Data w...
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2025-02-01
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| Series: | Tropical Medicine and Health |
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| Online Access: | https://doi.org/10.1186/s41182-025-00692-x |
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| author | Fatemeh Amiri Saeid Safiri Reza Aletaha Mark J. M. Sullman Kamaleddin Hassanzadeh Ali-Asghar Kolahi Shahnam Arshi |
| author_facet | Fatemeh Amiri Saeid Safiri Reza Aletaha Mark J. M. Sullman Kamaleddin Hassanzadeh Ali-Asghar Kolahi Shahnam Arshi |
| author_sort | Fatemeh Amiri |
| collection | DOAJ |
| description | Abstract Objective This research reports the incidence, mortality, and disability-adjusted life years (DALYs) associated with urinary tract infections (UTIs) in the Middle East and North Africa (MENA) region, stratified by sex, age, and Socio-demographic Index (SDI) from 1990 to 2021. Methods Data were sourced from the Global Burden of Disease 2021 study, encompassing all 21 countries in the region. Metrics such as absolute counts, age-standardised rates, and percentage changes from 1990 to 2021 are presented with 95% uncertainty intervals (UIs). Results In 2019, the MENA region recorded an incidence rate of 4,033.4 per 100,000 (95% UIs: 3,553.7–4,548.7) and 7,687 deaths (95% UIs: 6,663–8,969). The DALY rate was 41.3 per 100,000 (95% UIs: 36.1–47.2), which was highest among older adults, reaching a peak in the 80–89 age range, and increasing with age, particularly from the 50 + age groups. A non-linear relationship was identified between the burden of UTIs and the SDI, with higher-than-expected rates in lower SDI countries such as Syria and Lebanon. Conclusion Despite a substantial increase in the total number of UTI cases and DALYs in the region from 1990 to 2021, the age-standardised rates remained stable. The larger burden in lower SDI countries highlights the urgent need for targeted public health interventions. Improving healthcare access and antibiotic stewardship is crucial to mitigating the growing burden of UTIs, particularly among older populations in the region. |
| format | Article |
| id | doaj-art-9a7385caa6b04715acc69db72043365d |
| institution | Kabale University |
| issn | 1349-4147 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Tropical Medicine and Health |
| spelling | doaj-art-9a7385caa6b04715acc69db72043365d2025-02-09T12:54:54ZengBMCTropical Medicine and Health1349-41472025-02-0153111410.1186/s41182-025-00692-xEpidemiology of urinary tract infections in the Middle East and North Africa, 1990–2021Fatemeh Amiri0Saeid Safiri1Reza Aletaha2Mark J. M. Sullman3Kamaleddin Hassanzadeh4Ali-Asghar Kolahi5Shahnam Arshi6Social Determinants of Health Research Center, Department of Community Medicine, Faculty of Medicine, Tabriz University of Medical SciencesSocial Determinants of Health Research Center, Department of Community Medicine, Faculty of Medicine, Tabriz University of Medical SciencesNeurosciences Research Center, Aging Research Institute, Tabriz University of Medical SciencesDepartment of Life and Health Sciences, University of NicosiaDepartment of Urology, Faculty of Medicine, Tabriz University of Medical SciencesSocial Determinants of Health Research Center, Shahid Beheshti University of Medical SciencesSocial Determinants of Health Research Center, Shahid Beheshti University of Medical SciencesAbstract Objective This research reports the incidence, mortality, and disability-adjusted life years (DALYs) associated with urinary tract infections (UTIs) in the Middle East and North Africa (MENA) region, stratified by sex, age, and Socio-demographic Index (SDI) from 1990 to 2021. Methods Data were sourced from the Global Burden of Disease 2021 study, encompassing all 21 countries in the region. Metrics such as absolute counts, age-standardised rates, and percentage changes from 1990 to 2021 are presented with 95% uncertainty intervals (UIs). Results In 2019, the MENA region recorded an incidence rate of 4,033.4 per 100,000 (95% UIs: 3,553.7–4,548.7) and 7,687 deaths (95% UIs: 6,663–8,969). The DALY rate was 41.3 per 100,000 (95% UIs: 36.1–47.2), which was highest among older adults, reaching a peak in the 80–89 age range, and increasing with age, particularly from the 50 + age groups. A non-linear relationship was identified between the burden of UTIs and the SDI, with higher-than-expected rates in lower SDI countries such as Syria and Lebanon. Conclusion Despite a substantial increase in the total number of UTI cases and DALYs in the region from 1990 to 2021, the age-standardised rates remained stable. The larger burden in lower SDI countries highlights the urgent need for targeted public health interventions. Improving healthcare access and antibiotic stewardship is crucial to mitigating the growing burden of UTIs, particularly among older populations in the region.https://doi.org/10.1186/s41182-025-00692-xUrinary tract infectionsIncidenceMortalityGlobalEpidemiology |
| spellingShingle | Fatemeh Amiri Saeid Safiri Reza Aletaha Mark J. M. Sullman Kamaleddin Hassanzadeh Ali-Asghar Kolahi Shahnam Arshi Epidemiology of urinary tract infections in the Middle East and North Africa, 1990–2021 Tropical Medicine and Health Urinary tract infections Incidence Mortality Global Epidemiology |
| title | Epidemiology of urinary tract infections in the Middle East and North Africa, 1990–2021 |
| title_full | Epidemiology of urinary tract infections in the Middle East and North Africa, 1990–2021 |
| title_fullStr | Epidemiology of urinary tract infections in the Middle East and North Africa, 1990–2021 |
| title_full_unstemmed | Epidemiology of urinary tract infections in the Middle East and North Africa, 1990–2021 |
| title_short | Epidemiology of urinary tract infections in the Middle East and North Africa, 1990–2021 |
| title_sort | epidemiology of urinary tract infections in the middle east and north africa 1990 2021 |
| topic | Urinary tract infections Incidence Mortality Global Epidemiology |
| url | https://doi.org/10.1186/s41182-025-00692-x |
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