Investigation of human infection with H5N6 avian influenza cases in Sichuan Province from 2014 to 2024: a retrospective study
ObjectiveThe objective is to examine the epidemiology and clinical features of human cases infected with H5N6 avian influenza in Sichuan Province from 2014 to 2024, and to offer guidance for the prevention and management of human infections with H5N6 avian influenza.MethodsEpidemiological survey rep...
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Frontiers Media S.A.
2025-06-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1603158/full |
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| author | Lijun Zhou Zhirui Li Xingyu Zhou Lin Zhao Huanwen Peng Xunbo Du Jianping Yang Fengmiao Hu Shuang Dong Baisong Li Guidan Liu Hongyu Tang Xiao Lei Xiaojuan Wang Shunning Zhao Ping Zhou Heng Yuan Chongkun Xiao |
| author_facet | Lijun Zhou Zhirui Li Xingyu Zhou Lin Zhao Huanwen Peng Xunbo Du Jianping Yang Fengmiao Hu Shuang Dong Baisong Li Guidan Liu Hongyu Tang Xiao Lei Xiaojuan Wang Shunning Zhao Ping Zhou Heng Yuan Chongkun Xiao |
| author_sort | Lijun Zhou |
| collection | DOAJ |
| description | ObjectiveThe objective is to examine the epidemiology and clinical features of human cases infected with H5N6 avian influenza in Sichuan Province from 2014 to 2024, and to offer guidance for the prevention and management of human infections with H5N6 avian influenza.MethodsEpidemiological survey reports of H5N6 avian influenza cases in Sichuan Province from 2014 to 2024 were compiled, and the epidemiological context and characteristics of 16 human cases infected with H5N6 avian influenza in the province were summarized and analyzed using descriptive epidemiological methods.ResultsFrom 2014, when the initial human case ofH5N6 infection was documented in Sichuan Province, to 2024, there have been 16 human cases of H5N6 avian influenza in the region, resulting in 12 fatalities and a case fatality rate of 75%. The instances were predominantly located in the Chengdu Plain, eastern Sichuan, and southern Sichuan.ConclusionHuman instances of H5N6 avian influenza in Sichuan Province exhibit no discernible periodicity, and entail significant fatality rates. It is essential to enhance the early diagnosis and treatment of avian influenza cases in medical facilities, prioritize farmers with preexisting conditions who have been in contact with deceased poultry, conduct influenza virus testing promptly, and administer antiviral medications at the earliest opportunity. Simultaneously, we must effectively engage in public awareness and education for the populace, manage poultry scientifically, and prevent direct contact with deceased poultries. |
| format | Article |
| id | doaj-art-9a6d5d699f504de9b50f272710d1f0eb |
| institution | OA Journals |
| issn | 2296-2565 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj-art-9a6d5d699f504de9b50f272710d1f0eb2025-08-20T02:32:34ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-06-011310.3389/fpubh.2025.16031581603158Investigation of human infection with H5N6 avian influenza cases in Sichuan Province from 2014 to 2024: a retrospective studyLijun Zhou0Zhirui Li1Xingyu Zhou2Lin Zhao3Huanwen Peng4Xunbo Du5Jianping Yang6Fengmiao Hu7Shuang Dong8Baisong Li9Guidan Liu10Hongyu Tang11Xiao Lei12Xiaojuan Wang13Shunning Zhao14Ping Zhou15Heng Yuan16Chongkun Xiao17Department of Disease Control and Prevention, Sichuan Provincial Center for Disease Control and Prevention, Chengdu, ChinaDepartment of Disease Control and Prevention, Sichuan Provincial Center for Disease Control and Prevention, Chengdu, ChinaDepartment of Disease Control and Prevention, Sichuan Provincial Center for Disease Control and Prevention, Chengdu, ChinaNanchong Center for Disease Control and Prevention, Nanchong, ChinaDazhou Center for Disease Control and Prevention, Nanchong, ChinaChengdu Center for Disease Control and Prevention, Chengdu, ChinaBazhong Center for Disease Control and Prevention, Bazhong, ChinaDepartment of Disease Control and Prevention, Sichuan Provincial Center for Disease Control and Prevention, Chengdu, ChinaDepartment of Disease Control and Prevention, Sichuan Provincial Center for Disease Control and Prevention, Chengdu, ChinaChongqing Center for Disease Control and Prevention, Chongqing, ChinaZigong Center for Disease Control and Prevention, Zigong, ChinaDeyang Center for Disease Control and Prevention, Deyang, ChinaLeshan Municipal Center for Disease Control and Prevention, Leshan, China0Luzhou Center for Disease Control and Prevention, Luzhou, China1Ziyang Center for Disease Control and Prevention, Ziyang, China2Yibin Center for Disease Control and Prevention, Yibin, ChinaDepartment of Disease Control and Prevention, Sichuan Provincial Center for Disease Control and Prevention, Chengdu, ChinaDepartment of Disease Control and Prevention, Sichuan Provincial Center for Disease Control and Prevention, Chengdu, ChinaObjectiveThe objective is to examine the epidemiology and clinical features of human cases infected with H5N6 avian influenza in Sichuan Province from 2014 to 2024, and to offer guidance for the prevention and management of human infections with H5N6 avian influenza.MethodsEpidemiological survey reports of H5N6 avian influenza cases in Sichuan Province from 2014 to 2024 were compiled, and the epidemiological context and characteristics of 16 human cases infected with H5N6 avian influenza in the province were summarized and analyzed using descriptive epidemiological methods.ResultsFrom 2014, when the initial human case ofH5N6 infection was documented in Sichuan Province, to 2024, there have been 16 human cases of H5N6 avian influenza in the region, resulting in 12 fatalities and a case fatality rate of 75%. The instances were predominantly located in the Chengdu Plain, eastern Sichuan, and southern Sichuan.ConclusionHuman instances of H5N6 avian influenza in Sichuan Province exhibit no discernible periodicity, and entail significant fatality rates. It is essential to enhance the early diagnosis and treatment of avian influenza cases in medical facilities, prioritize farmers with preexisting conditions who have been in contact with deceased poultry, conduct influenza virus testing promptly, and administer antiviral medications at the earliest opportunity. Simultaneously, we must effectively engage in public awareness and education for the populace, manage poultry scientifically, and prevent direct contact with deceased poultries.https://www.frontiersin.org/articles/10.3389/fpubh.2025.1603158/fullinfluenzaepidemiologyavianH5N6poultry diseases |
| spellingShingle | Lijun Zhou Zhirui Li Xingyu Zhou Lin Zhao Huanwen Peng Xunbo Du Jianping Yang Fengmiao Hu Shuang Dong Baisong Li Guidan Liu Hongyu Tang Xiao Lei Xiaojuan Wang Shunning Zhao Ping Zhou Heng Yuan Chongkun Xiao Investigation of human infection with H5N6 avian influenza cases in Sichuan Province from 2014 to 2024: a retrospective study Frontiers in Public Health influenza epidemiology avian H5N6 poultry diseases |
| title | Investigation of human infection with H5N6 avian influenza cases in Sichuan Province from 2014 to 2024: a retrospective study |
| title_full | Investigation of human infection with H5N6 avian influenza cases in Sichuan Province from 2014 to 2024: a retrospective study |
| title_fullStr | Investigation of human infection with H5N6 avian influenza cases in Sichuan Province from 2014 to 2024: a retrospective study |
| title_full_unstemmed | Investigation of human infection with H5N6 avian influenza cases in Sichuan Province from 2014 to 2024: a retrospective study |
| title_short | Investigation of human infection with H5N6 avian influenza cases in Sichuan Province from 2014 to 2024: a retrospective study |
| title_sort | investigation of human infection with h5n6 avian influenza cases in sichuan province from 2014 to 2024 a retrospective study |
| topic | influenza epidemiology avian H5N6 poultry diseases |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1603158/full |
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