Fine-Tuning Reception in the Bone: PPARγ and Company
PPARγ plays a central role in the formation of fat. Regulation of PPARγ activity depends on numerous factors ranging from dietary ligands to nuclear hormone coactivators and corepressors to oxygen-sensing mechanisms. In addition, the interplay of PPARγ with other nuclear hormone receptors has implic...
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| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2006-01-01
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| Series: | PPAR Research |
| Online Access: | http://dx.doi.org/10.1155/PPAR/2006/52950 |
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| _version_ | 1832556119654924288 |
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| author | Z. Elizabeth Floyd Sanjin Zvonic Mark E. Nuttall Jeffrey M. Gimble |
| author_facet | Z. Elizabeth Floyd Sanjin Zvonic Mark E. Nuttall Jeffrey M. Gimble |
| author_sort | Z. Elizabeth Floyd |
| collection | DOAJ |
| description | PPARγ plays a central role in the formation of fat.
Regulation of PPARγ activity depends on numerous factors
ranging from dietary ligands to nuclear hormone coactivators and
corepressors to oxygen-sensing mechanisms. In addition, the
interplay of PPARγ with other nuclear hormone receptors
has implications for the balance between adipogenesis and
osteogenesis in mesenchymal stem cells of the bone marrow stroma.
This review will explore a range of factors influencing
PPARγ activity and how these interactions may affect
osteogenesis. |
| format | Article |
| id | doaj-art-9a6cdaba569e40f0a573f7a579e0cd60 |
| institution | Kabale University |
| issn | 1687-4757 1687-4765 |
| language | English |
| publishDate | 2006-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | PPAR Research |
| spelling | doaj-art-9a6cdaba569e40f0a573f7a579e0cd602025-02-03T05:46:20ZengWileyPPAR Research1687-47571687-47652006-01-01200610.1155/PPAR/2006/5295052950Fine-Tuning Reception in the Bone: PPARγ and CompanyZ. Elizabeth Floyd0Sanjin Zvonic1Mark E. Nuttall2Jeffrey M. Gimble3Stem Cell Laboratory, Pennington Biomedical Research Center, Baton Rouge 70808, LA, USAStem Cell Laboratory, Pennington Biomedical Research Center, Baton Rouge 70808, LA, USACentocor, Johnson and Johnson, Horsham 19044, PA, USAStem Cell Laboratory, Pennington Biomedical Research Center, Baton Rouge 70808, LA, USAPPARγ plays a central role in the formation of fat. Regulation of PPARγ activity depends on numerous factors ranging from dietary ligands to nuclear hormone coactivators and corepressors to oxygen-sensing mechanisms. In addition, the interplay of PPARγ with other nuclear hormone receptors has implications for the balance between adipogenesis and osteogenesis in mesenchymal stem cells of the bone marrow stroma. This review will explore a range of factors influencing PPARγ activity and how these interactions may affect osteogenesis.http://dx.doi.org/10.1155/PPAR/2006/52950 |
| spellingShingle | Z. Elizabeth Floyd Sanjin Zvonic Mark E. Nuttall Jeffrey M. Gimble Fine-Tuning Reception in the Bone: PPARγ and Company PPAR Research |
| title | Fine-Tuning Reception in the Bone: PPARγ and Company |
| title_full | Fine-Tuning Reception in the Bone: PPARγ and Company |
| title_fullStr | Fine-Tuning Reception in the Bone: PPARγ and Company |
| title_full_unstemmed | Fine-Tuning Reception in the Bone: PPARγ and Company |
| title_short | Fine-Tuning Reception in the Bone: PPARγ and Company |
| title_sort | fine tuning reception in the bone pparγ and company |
| url | http://dx.doi.org/10.1155/PPAR/2006/52950 |
| work_keys_str_mv | AT zelizabethfloyd finetuningreceptionintheboneppargandcompany AT sanjinzvonic finetuningreceptionintheboneppargandcompany AT markenuttall finetuningreceptionintheboneppargandcompany AT jeffreymgimble finetuningreceptionintheboneppargandcompany |