Invasive micropapillary carcinoma of the breast and bilateral ovarian mature cystic teratoma with benign Brenner tumor in a postmenopausal woman – An uncommon occurrence

The synchronous occurrence of bilateral ovarian tumors and breast malignancy often raise the suspicion of a Krukenberg tumor or a hereditary breast and ovarian cancer syndrome, both of which are uncommon in clinical practice. A 58-years-old postmenopausal woman had a right breast lump and was diagno...

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Main Authors: Pavithra Ayyanar, Suvradeep Mitra, Mohammed Imaduddin, Dillip K. Muduly
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Online Access:https://journals.lww.com/10.4103/ijpm.ijpm_1207_21
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author Pavithra Ayyanar
Suvradeep Mitra
Mohammed Imaduddin
Dillip K. Muduly
author_facet Pavithra Ayyanar
Suvradeep Mitra
Mohammed Imaduddin
Dillip K. Muduly
author_sort Pavithra Ayyanar
collection DOAJ
description The synchronous occurrence of bilateral ovarian tumors and breast malignancy often raise the suspicion of a Krukenberg tumor or a hereditary breast and ovarian cancer syndrome, both of which are uncommon in clinical practice. A 58-years-old postmenopausal woman had a right breast lump and was diagnosed as infiltrating duct carcinoma, no special type, and incidentally detected bilateral adnexal mass with the clinical suspicion of Krukenberg tumor. However, following the radical surgical excision of the right breast and bilateral ovaries, the right breast showed invasive micropapillary carcinoma (IMPC) while the ovaries showed mature cystic teratoma (MCT) with benign Brenner tumor. IMPC of the breast along with bilateral ovarian MCT with benign Brenner tumor is an unusual clinical occurrence in a postmenopausal female and thus worthy of documentation. It should be categorized as a non-hereditary synchronous tumor. The histomorphology augmented by immunohistochemistry and appropriate clinical context is pivotal in rendering a correct diagnosis.
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institution Kabale University
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publisher Wolters Kluwer Medknow Publications
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series Indian Journal of Pathology and Microbiology
spelling doaj-art-9a6c30bfd3094269af04d21be184b8922025-01-22T15:14:20ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302023-01-0167118819110.4103/ijpm.ijpm_1207_21Invasive micropapillary carcinoma of the breast and bilateral ovarian mature cystic teratoma with benign Brenner tumor in a postmenopausal woman – An uncommon occurrencePavithra AyyanarSuvradeep MitraMohammed ImaduddinDillip K. MudulyThe synchronous occurrence of bilateral ovarian tumors and breast malignancy often raise the suspicion of a Krukenberg tumor or a hereditary breast and ovarian cancer syndrome, both of which are uncommon in clinical practice. A 58-years-old postmenopausal woman had a right breast lump and was diagnosed as infiltrating duct carcinoma, no special type, and incidentally detected bilateral adnexal mass with the clinical suspicion of Krukenberg tumor. However, following the radical surgical excision of the right breast and bilateral ovaries, the right breast showed invasive micropapillary carcinoma (IMPC) while the ovaries showed mature cystic teratoma (MCT) with benign Brenner tumor. IMPC of the breast along with bilateral ovarian MCT with benign Brenner tumor is an unusual clinical occurrence in a postmenopausal female and thus worthy of documentation. It should be categorized as a non-hereditary synchronous tumor. The histomorphology augmented by immunohistochemistry and appropriate clinical context is pivotal in rendering a correct diagnosis.https://journals.lww.com/10.4103/ijpm.ijpm_1207_21brenner tumorgata3invasive micropapillary carcinomamature cystic teratomapostmenopausal female
spellingShingle Pavithra Ayyanar
Suvradeep Mitra
Mohammed Imaduddin
Dillip K. Muduly
Invasive micropapillary carcinoma of the breast and bilateral ovarian mature cystic teratoma with benign Brenner tumor in a postmenopausal woman – An uncommon occurrence
Indian Journal of Pathology and Microbiology
brenner tumor
gata3
invasive micropapillary carcinoma
mature cystic teratoma
postmenopausal female
title Invasive micropapillary carcinoma of the breast and bilateral ovarian mature cystic teratoma with benign Brenner tumor in a postmenopausal woman – An uncommon occurrence
title_full Invasive micropapillary carcinoma of the breast and bilateral ovarian mature cystic teratoma with benign Brenner tumor in a postmenopausal woman – An uncommon occurrence
title_fullStr Invasive micropapillary carcinoma of the breast and bilateral ovarian mature cystic teratoma with benign Brenner tumor in a postmenopausal woman – An uncommon occurrence
title_full_unstemmed Invasive micropapillary carcinoma of the breast and bilateral ovarian mature cystic teratoma with benign Brenner tumor in a postmenopausal woman – An uncommon occurrence
title_short Invasive micropapillary carcinoma of the breast and bilateral ovarian mature cystic teratoma with benign Brenner tumor in a postmenopausal woman – An uncommon occurrence
title_sort invasive micropapillary carcinoma of the breast and bilateral ovarian mature cystic teratoma with benign brenner tumor in a postmenopausal woman an uncommon occurrence
topic brenner tumor
gata3
invasive micropapillary carcinoma
mature cystic teratoma
postmenopausal female
url https://journals.lww.com/10.4103/ijpm.ijpm_1207_21
work_keys_str_mv AT pavithraayyanar invasivemicropapillarycarcinomaofthebreastandbilateralovarianmaturecysticteratomawithbenignbrennertumorinapostmenopausalwomananuncommonoccurrence
AT suvradeepmitra invasivemicropapillarycarcinomaofthebreastandbilateralovarianmaturecysticteratomawithbenignbrennertumorinapostmenopausalwomananuncommonoccurrence
AT mohammedimaduddin invasivemicropapillarycarcinomaofthebreastandbilateralovarianmaturecysticteratomawithbenignbrennertumorinapostmenopausalwomananuncommonoccurrence
AT dillipkmuduly invasivemicropapillarycarcinomaofthebreastandbilateralovarianmaturecysticteratomawithbenignbrennertumorinapostmenopausalwomananuncommonoccurrence