Synthesis of Novel Diclofenac Hydrazones: Molecular Docking, Anti-Inflammatory, Analgesic, and Ulcerogenic Activity

This study was aimed to design novel diclofenac hydrazones having anti-inflammatory and analgesic activity with gastric sparing effect. A new series of 2-[2-(2,6-dichloroanilino)phenyl]-N’-[(substituted phenyl) methylidene] acetohydrazide derivatives (1−14) were synthesized and evaluated for their a...

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Bibliographic Details
Main Authors: Nawaf A. Alsaif, Mashooq A. Bhat, Mohamed A. Al-Omar, Hanaa M. Al-Tuwajiri, Ahmed M. Naglah, Abdullah Al-Dhfyan
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2020/4916726
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