Plexiform neurofibromas of bilateral brachial and lumbosacral plexuses

Plexiform neurofibroma is a peripheral nerve sheath tumor that involves multiple nerve fascicles or nerve branches and is considered to be pathognomic of neurofibromatosis type-1. They are often large lesions which can distort the nerves and are most commonly reported in the craniomaxillofacial regi...

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Main Authors: S Sheetal, S Vijayalekshmi, Aswathy Sasidharan, N Jisa Merin Joy
Format: Article
Language:English
Published: SAGE Publishing 2022-01-01
Series:Apollo Medicine
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Online Access:http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2022;volume=19;issue=5;spage=11;epage=13;aulast=Sheetal
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author S Sheetal
S Vijayalekshmi
Aswathy Sasidharan
N Jisa Merin Joy
author_facet S Sheetal
S Vijayalekshmi
Aswathy Sasidharan
N Jisa Merin Joy
author_sort S Sheetal
collection DOAJ
description Plexiform neurofibroma is a peripheral nerve sheath tumor that involves multiple nerve fascicles or nerve branches and is considered to be pathognomic of neurofibromatosis type-1. They are often large lesions which can distort the nerves and are most commonly reported in the craniomaxillofacial region. We are reporting plexiform neurofibroma of bilateral brachial and lumbosacral plexuses, which is rarely reported, with only three cases being reported so far. A 33-year-old woman presented with complaints of dragging of the right lower limb on walking, for the past 6 months and on examination, was noted to have features of cervical myelopathy. Magnetic resonance imaging of the spine showed multiple lesions of the cervical exiting nerve roots bilaterally, with extension along the brachial plexus and lesions along the lumbar plexus on both sides suggestive of plexiform neurofibroma. Considering the lack of feasibility of complete resection, surgery was not considered and she was advised to be under follow-up. Plexiform neurofibromas are large lesions arising from peripheral nerves and can cause symptoms due to the compression of adjacent structures. Plexiform neurofibroma involving brachial and lumbosacral plexuses on both sides is very rarely reported, with only three cases being reported so far.
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spelling doaj-art-9a65f74be20c4ae79a1fe7cd856e08942025-08-20T02:00:38ZengSAGE PublishingApollo Medicine0976-00162213-36822022-01-01195111310.4103/am.am_22_22Plexiform neurofibromas of bilateral brachial and lumbosacral plexusesS SheetalS VijayalekshmiAswathy SasidharanN Jisa Merin JoyPlexiform neurofibroma is a peripheral nerve sheath tumor that involves multiple nerve fascicles or nerve branches and is considered to be pathognomic of neurofibromatosis type-1. They are often large lesions which can distort the nerves and are most commonly reported in the craniomaxillofacial region. We are reporting plexiform neurofibroma of bilateral brachial and lumbosacral plexuses, which is rarely reported, with only three cases being reported so far. A 33-year-old woman presented with complaints of dragging of the right lower limb on walking, for the past 6 months and on examination, was noted to have features of cervical myelopathy. Magnetic resonance imaging of the spine showed multiple lesions of the cervical exiting nerve roots bilaterally, with extension along the brachial plexus and lesions along the lumbar plexus on both sides suggestive of plexiform neurofibroma. Considering the lack of feasibility of complete resection, surgery was not considered and she was advised to be under follow-up. Plexiform neurofibromas are large lesions arising from peripheral nerves and can cause symptoms due to the compression of adjacent structures. Plexiform neurofibroma involving brachial and lumbosacral plexuses on both sides is very rarely reported, with only three cases being reported so far.http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2022;volume=19;issue=5;spage=11;epage=13;aulast=Sheetalbrachial plexuscompressive myelopathylumbosacral plexusplexiform neurofibromas
spellingShingle S Sheetal
S Vijayalekshmi
Aswathy Sasidharan
N Jisa Merin Joy
Plexiform neurofibromas of bilateral brachial and lumbosacral plexuses
Apollo Medicine
brachial plexus
compressive myelopathy
lumbosacral plexus
plexiform neurofibromas
title Plexiform neurofibromas of bilateral brachial and lumbosacral plexuses
title_full Plexiform neurofibromas of bilateral brachial and lumbosacral plexuses
title_fullStr Plexiform neurofibromas of bilateral brachial and lumbosacral plexuses
title_full_unstemmed Plexiform neurofibromas of bilateral brachial and lumbosacral plexuses
title_short Plexiform neurofibromas of bilateral brachial and lumbosacral plexuses
title_sort plexiform neurofibromas of bilateral brachial and lumbosacral plexuses
topic brachial plexus
compressive myelopathy
lumbosacral plexus
plexiform neurofibromas
url http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2022;volume=19;issue=5;spage=11;epage=13;aulast=Sheetal
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AT aswathysasidharan plexiformneurofibromasofbilateralbrachialandlumbosacralplexuses
AT njisamerinjoy plexiformneurofibromasofbilateralbrachialandlumbosacralplexuses