Moderate intensity continuous training mitigates hypertension-induced renal fibrosis by inhibiting HIF-1α-mediated autophagy

Moderate intensity continuous training mitigates hypertension-induced renal fibrosis by inhibiting HIF-1α-mediated autophagy

Introduction: Hypertension is a significant risk factor for kidney disease. Aerobic exercise has demonstrated positive effects in managing hypertensive nephropathy. However, the impact of exercise on hypertensive nephropathy remains contentious due to variations in exercise protocols. This study aim...

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Bibliographic Details
Main Authors: Yun Li, Xinyu Yang, Zhuo Chen, Wenyu Dong, Xinhua Chen, Wenhao Wang, Lingang Li, Wenjun Ma, Qing Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Physiology
Subjects:
moderate intensity continuous training
HIF-1α
autophagy
hypertensive renal fibrosis
high-intensity interval training
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1529811/full
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