Assessing equity in preventing central line-associated bloodstream infections and surgical site infections in pediatric patients
Abstract Background: Central line-associated bloodstream infections (CLABSIs) and surgical site infections (SSIs) are major healthcare-associated infections that can be prevented by consistently applying evidence-based infection prevention practices. Objective: To assess equity in preventing CLA...
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2025-01-01
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| Series: | Antimicrobial Stewardship & Healthcare Epidemiology |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2732494X24005023/type/journal_article |
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| author | Xiaoyan Song Deena Levey Jenhao Jacob Cheng Monica Monteon Annette Lee Nada Harik Denice Cora-Bramble Rahul K. Shah |
| author_facet | Xiaoyan Song Deena Levey Jenhao Jacob Cheng Monica Monteon Annette Lee Nada Harik Denice Cora-Bramble Rahul K. Shah |
| author_sort | Xiaoyan Song |
| collection | DOAJ |
| description |
Abstract
Background:
Central line-associated bloodstream infections (CLABSIs) and surgical site infections (SSIs) are major healthcare-associated infections that can be prevented by consistently applying evidence-based infection prevention practices.
Objective:
To assess equity in preventing CLABSIs and SSIs in pediatric patients at a free-standing pediatric hospital, where evidence-based infection prevention practices are consistently implemented.
Methods:
This observational study evaluated 2 cohorts of pediatric patients under 18 years. The CLABSI cohort included inpatients with a central line between 1/1/2016 and 12/31/2022, and the SSI cohort included patients undergoing colon, ventricular shunt, or spinal fusion surgeries between 1/1/2016 and 10/31/2022. The CLABSI rate per 1000 central line days and SSI rate per 100 surgeries were compared across different racial, ethnic, and gender groups.
Results:
In the CLABSI cohort of 8575 patients, encompassing 243,803 central line days, there were 156 CLABSIs. There was no statistical difference in CLABSI rate across race, ethnicity, and/or gender groups. The SSI cohort included 68 SSIs among 1710 patients who underwent 2230 procedures, including 714 colon, 749 ventricular shunt, and 767 spinal fusion procedures. The SSI rate was statistically higher in multiracial (9.9) and Asian (8.6) groups, compared to Caucasian (2.4) and Black (2.2) groups. A nested case-control study of the SSI cohort showed a higher SSI rate in Asians, compared to Caucasians (Odds Ratio: 3.3; 95% CI: 1.3–8.3).
Conclusions:
Equity in preventing CLABSIs is achievable through standardized central-line care. Further study is warranted to assess if improvement opportunities exist for achieving equity in preventing SSIs.
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| format | Article |
| id | doaj-art-9a5998edf5b241158ac2745c48af473f |
| institution | Kabale University |
| issn | 2732-494X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Antimicrobial Stewardship & Healthcare Epidemiology |
| spelling | doaj-art-9a5998edf5b241158ac2745c48af473f2025-01-27T10:13:07ZengCambridge University PressAntimicrobial Stewardship & Healthcare Epidemiology2732-494X2025-01-01510.1017/ash.2024.502Assessing equity in preventing central line-associated bloodstream infections and surgical site infections in pediatric patientsXiaoyan Song0https://orcid.org/0000-0002-4907-0566Deena Levey1Jenhao Jacob Cheng2https://orcid.org/0000-0001-8359-2475Monica Monteon3Annette Lee4Nada Harik5Denice Cora-Bramble6Rahul K. Shah7Office of Infection Control/Epidemiology, Children’s National Hospital, Washington, DC, USA The George Washington University, Washington, DC, USAOffice of Infection Control/Epidemiology, Children’s National Hospital, Washington, DC, USADepartment of Quality & Patient Safety, Children’s National Hospital, Washington, DC, USAOffice of Infection Control/Epidemiology, Children’s National Hospital, Washington, DC, USAOffice of Infection Control/Epidemiology, Children’s National Hospital, Washington, DC, USAThe George Washington University, Washington, DC, USAThe George Washington University, Washington, DC, USAAmerican Academy of Otolaryngology-Head & Neck Surgery, Alexandria, VA, USA Abstract Background: Central line-associated bloodstream infections (CLABSIs) and surgical site infections (SSIs) are major healthcare-associated infections that can be prevented by consistently applying evidence-based infection prevention practices. Objective: To assess equity in preventing CLABSIs and SSIs in pediatric patients at a free-standing pediatric hospital, where evidence-based infection prevention practices are consistently implemented. Methods: This observational study evaluated 2 cohorts of pediatric patients under 18 years. The CLABSI cohort included inpatients with a central line between 1/1/2016 and 12/31/2022, and the SSI cohort included patients undergoing colon, ventricular shunt, or spinal fusion surgeries between 1/1/2016 and 10/31/2022. The CLABSI rate per 1000 central line days and SSI rate per 100 surgeries were compared across different racial, ethnic, and gender groups. Results: In the CLABSI cohort of 8575 patients, encompassing 243,803 central line days, there were 156 CLABSIs. There was no statistical difference in CLABSI rate across race, ethnicity, and/or gender groups. The SSI cohort included 68 SSIs among 1710 patients who underwent 2230 procedures, including 714 colon, 749 ventricular shunt, and 767 spinal fusion procedures. The SSI rate was statistically higher in multiracial (9.9) and Asian (8.6) groups, compared to Caucasian (2.4) and Black (2.2) groups. A nested case-control study of the SSI cohort showed a higher SSI rate in Asians, compared to Caucasians (Odds Ratio: 3.3; 95% CI: 1.3–8.3). Conclusions: Equity in preventing CLABSIs is achievable through standardized central-line care. Further study is warranted to assess if improvement opportunities exist for achieving equity in preventing SSIs. https://www.cambridge.org/core/product/identifier/S2732494X24005023/type/journal_article |
| spellingShingle | Xiaoyan Song Deena Levey Jenhao Jacob Cheng Monica Monteon Annette Lee Nada Harik Denice Cora-Bramble Rahul K. Shah Assessing equity in preventing central line-associated bloodstream infections and surgical site infections in pediatric patients Antimicrobial Stewardship & Healthcare Epidemiology |
| title | Assessing equity in preventing central line-associated bloodstream infections and surgical site infections in pediatric patients |
| title_full | Assessing equity in preventing central line-associated bloodstream infections and surgical site infections in pediatric patients |
| title_fullStr | Assessing equity in preventing central line-associated bloodstream infections and surgical site infections in pediatric patients |
| title_full_unstemmed | Assessing equity in preventing central line-associated bloodstream infections and surgical site infections in pediatric patients |
| title_short | Assessing equity in preventing central line-associated bloodstream infections and surgical site infections in pediatric patients |
| title_sort | assessing equity in preventing central line associated bloodstream infections and surgical site infections in pediatric patients |
| url | https://www.cambridge.org/core/product/identifier/S2732494X24005023/type/journal_article |
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