Chemical analysis, repellent, larvicidal, and oviposition deterrent activities of plant essential oils against Aedes aegypti, Anopheles gambiae, and Culex quinquefasciatus

Plant-based essential oils have gained attention as a natural alternative for controlling mosquitoes due to their repellent, larvicidal and oviposition deterrent properties. We tested repellent, larvicidal, and oviposition deterrent effects of essential oils (EOs) of Mentha spicata (L.), Ocimum basi...

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Main Authors: Muhammad Ghazanfar Abbas, Muhammad Binyameen, Muhammad Azeem, Shahid Majeed, Zahid Mehmood Sarwar, Abdul Nazir, Mahar Muhammad Imran Sharif, Amna Parveen, Raimondas Mozūratis
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Insect Science
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Online Access:https://www.frontiersin.org/articles/10.3389/finsc.2025.1582669/full
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author Muhammad Ghazanfar Abbas
Muhammad Binyameen
Muhammad Azeem
Shahid Majeed
Zahid Mehmood Sarwar
Abdul Nazir
Mahar Muhammad Imran Sharif
Amna Parveen
Raimondas Mozūratis
Raimondas Mozūratis
author_facet Muhammad Ghazanfar Abbas
Muhammad Binyameen
Muhammad Azeem
Shahid Majeed
Zahid Mehmood Sarwar
Abdul Nazir
Mahar Muhammad Imran Sharif
Amna Parveen
Raimondas Mozūratis
Raimondas Mozūratis
author_sort Muhammad Ghazanfar Abbas
collection DOAJ
description Plant-based essential oils have gained attention as a natural alternative for controlling mosquitoes due to their repellent, larvicidal and oviposition deterrent properties. We tested repellent, larvicidal, and oviposition deterrent effects of essential oils (EOs) of Mentha spicata (L.), Ocimum basilicum (L.), and Abutilon indicum (L.) against three mosquito species (Diptera: Culicidae) including Aedes aegypti (L.), Anopheles gambiae s. l. Giles, and Culex quinquefasciatus Say by using contact-based technique. In screening bioassays, M. spicata I, M. spicata II, O. basilicum I, O. basilicum II, and A. indicum EOs showed higher repellency against Cx. quinquefasciatus as compared to Ae. aegypti and An. gambiae when tested at 33.3 μg/cm2. In time-span bioassays performed at 33.3 μg/cm2, EO of M. spicata I exhibited 100% repellence up to 45, 30, and 75 min against Ae. aegypti, An. gambiae, and Cx. quinquefasciatus, respectively. Interestingly, at this tested dose, M. spicata I and M. spicata II showed higher repellence compared to DEET against Ae. aegypti and Cx. quinquefasciatus after 45 and 75 min, respectively. Their repellency was observed up to 150 and 210 min against Ae. aegypti and Cx. quinquefasciatus, respectively. In larvicidal bioassays, M. spicata I EO proved more toxic against 2nd instar larvae of Ae. aegypti, An. gambiae, and Cx. quinquefasciatus (LC50 = 11.0, 42.9, and 12.6 mg/L, respectively) compared to other tested EOs. In oviposition bioassays, M. spicata I exhibited the highest activity, showing 60%, 46%, and 79% oviposition deterrence against Ae. aegypti, An. gambiae, and Cx. quinquefasciatus, respectively, tested at a dose of 600 µg/cm2. Major compounds of M. spicata I, M. spicata II, O. basilicum I, and O. basilicum II EOs were piperitenone oxide (38.8%), piperitone oxide (35.4%), estragole (55.3%), and linalool (43.8%), respectively. In conclusion, M. spicata EO could be used to control mosquitoes and their bites.
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spelling doaj-art-9a3bace10ca24ebeb781fd99f9f1db282025-08-20T03:10:11ZengFrontiers Media S.A.Frontiers in Insect Science2673-86002025-05-01510.3389/finsc.2025.15826691582669Chemical analysis, repellent, larvicidal, and oviposition deterrent activities of plant essential oils against Aedes aegypti, Anopheles gambiae, and Culex quinquefasciatusMuhammad Ghazanfar Abbas0Muhammad Binyameen1Muhammad Azeem2Shahid Majeed3Zahid Mehmood Sarwar4Abdul Nazir5Mahar Muhammad Imran Sharif6Amna Parveen7Raimondas Mozūratis8Raimondas Mozūratis9Laboratory of Insect Chemical Ecology, Department of Entomology, Faculty of Agricultural Sciences & Technology, Bahauddin Zakariya University, Multan, PakistanLaboratory of Insect Chemical Ecology, Department of Entomology, Faculty of Agricultural Sciences & Technology, Bahauddin Zakariya University, Multan, PakistanDepartment of Chemistry, COMSATS University Islamabad, Abbottabad, PakistanDepartment of Entomology, University of Agriculture, Faisalabad, PakistanLaboratory of Insect Chemical Ecology, Department of Entomology, Faculty of Agricultural Sciences & Technology, Bahauddin Zakariya University, Multan, PakistanDepartment of Environmental Sciences, COMSATS University Islamabad, Abbottabad, PakistanLaboratory of Insect Chemical Ecology, Department of Entomology, Faculty of Agricultural Sciences & Technology, Bahauddin Zakariya University, Multan, PakistanDepartment of Chemistry, COMSATS University Islamabad, Abbottabad, PakistanLaboratory of Chemical and Behavioural Ecology, Institute of Ecology, State Scientific Research Institute Nature Research Centre, Vilnius, LithuaniaDepartment of Zoology, Stockholm University, Stockholm, SwedenPlant-based essential oils have gained attention as a natural alternative for controlling mosquitoes due to their repellent, larvicidal and oviposition deterrent properties. We tested repellent, larvicidal, and oviposition deterrent effects of essential oils (EOs) of Mentha spicata (L.), Ocimum basilicum (L.), and Abutilon indicum (L.) against three mosquito species (Diptera: Culicidae) including Aedes aegypti (L.), Anopheles gambiae s. l. Giles, and Culex quinquefasciatus Say by using contact-based technique. In screening bioassays, M. spicata I, M. spicata II, O. basilicum I, O. basilicum II, and A. indicum EOs showed higher repellency against Cx. quinquefasciatus as compared to Ae. aegypti and An. gambiae when tested at 33.3 μg/cm2. In time-span bioassays performed at 33.3 μg/cm2, EO of M. spicata I exhibited 100% repellence up to 45, 30, and 75 min against Ae. aegypti, An. gambiae, and Cx. quinquefasciatus, respectively. Interestingly, at this tested dose, M. spicata I and M. spicata II showed higher repellence compared to DEET against Ae. aegypti and Cx. quinquefasciatus after 45 and 75 min, respectively. Their repellency was observed up to 150 and 210 min against Ae. aegypti and Cx. quinquefasciatus, respectively. In larvicidal bioassays, M. spicata I EO proved more toxic against 2nd instar larvae of Ae. aegypti, An. gambiae, and Cx. quinquefasciatus (LC50 = 11.0, 42.9, and 12.6 mg/L, respectively) compared to other tested EOs. In oviposition bioassays, M. spicata I exhibited the highest activity, showing 60%, 46%, and 79% oviposition deterrence against Ae. aegypti, An. gambiae, and Cx. quinquefasciatus, respectively, tested at a dose of 600 µg/cm2. Major compounds of M. spicata I, M. spicata II, O. basilicum I, and O. basilicum II EOs were piperitenone oxide (38.8%), piperitone oxide (35.4%), estragole (55.3%), and linalool (43.8%), respectively. In conclusion, M. spicata EO could be used to control mosquitoes and their bites.https://www.frontiersin.org/articles/10.3389/finsc.2025.1582669/fullrepellencechemical constituentsmentha spicatacontrol strategieseco-friendlygas chromatography-mass spectrometry
spellingShingle Muhammad Ghazanfar Abbas
Muhammad Binyameen
Muhammad Azeem
Shahid Majeed
Zahid Mehmood Sarwar
Abdul Nazir
Mahar Muhammad Imran Sharif
Amna Parveen
Raimondas Mozūratis
Raimondas Mozūratis
Chemical analysis, repellent, larvicidal, and oviposition deterrent activities of plant essential oils against Aedes aegypti, Anopheles gambiae, and Culex quinquefasciatus
Frontiers in Insect Science
repellence
chemical constituents
mentha spicata
control strategies
eco-friendly
gas chromatography-mass spectrometry
title Chemical analysis, repellent, larvicidal, and oviposition deterrent activities of plant essential oils against Aedes aegypti, Anopheles gambiae, and Culex quinquefasciatus
title_full Chemical analysis, repellent, larvicidal, and oviposition deterrent activities of plant essential oils against Aedes aegypti, Anopheles gambiae, and Culex quinquefasciatus
title_fullStr Chemical analysis, repellent, larvicidal, and oviposition deterrent activities of plant essential oils against Aedes aegypti, Anopheles gambiae, and Culex quinquefasciatus
title_full_unstemmed Chemical analysis, repellent, larvicidal, and oviposition deterrent activities of plant essential oils against Aedes aegypti, Anopheles gambiae, and Culex quinquefasciatus
title_short Chemical analysis, repellent, larvicidal, and oviposition deterrent activities of plant essential oils against Aedes aegypti, Anopheles gambiae, and Culex quinquefasciatus
title_sort chemical analysis repellent larvicidal and oviposition deterrent activities of plant essential oils against aedes aegypti anopheles gambiae and culex quinquefasciatus
topic repellence
chemical constituents
mentha spicata
control strategies
eco-friendly
gas chromatography-mass spectrometry
url https://www.frontiersin.org/articles/10.3389/finsc.2025.1582669/full
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