CPP-calcification of articular cartilage is associated with elevated cytokine levels in synovial fluid

CPP-calcification of articular cartilage is associated with elevated cytokine levels in synovial fluid

BackgroundCalcification of articular tissues is commonly observed in later osteoarthritis (OA) stages and can be caused by basic calcium phosphate (BCP) or calcium pyrophosphate (CPP) crystals. Calcification, particularly CPP deposition, has recently been associated with inflammation and cellular se...

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Bibliographic Details
Main Authors: Sina Stücker, Franziska Koßlowksi, Adrian Buchholz, Andrea Schwab, Agnieszka Halm-Pozniak, Christoph H. Lohmann, Jessica Bertrand
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
calcification
cartilage
synovial fluid
senescence
calcium crystals
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1535530/full
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