Morphology and thermal stability of silk fibroin/starch blended microparticles

In the present study biodegradable microparticles of silk fibroin (SF)/starch blends were prepared by a simple water-in-oil emulsion solvent diffusion technique. SF/starch blended solution and ethyl acetate were used as water and oil phases, respectively. The influence of SF/starch ratios on charact...

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Format: Article
Language:English
Published: Budapest University of Technology and Economics 2010-12-01
Series:eXPRESS Polymer Letters
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Online Access:http://www.expresspolymlett.com/letolt.php?file=EPL-0001683&mi=cd
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description In the present study biodegradable microparticles of silk fibroin (SF)/starch blends were prepared by a simple water-in-oil emulsion solvent diffusion technique. SF/starch blended solution and ethyl acetate were used as water and oil phases, respectively. The influence of SF/starch ratios on characteristics of the blended microparticles was investigated. The SF conformation of microparticle matrices from FTIR analysis was changed from random coil to β-sheet form by blending with starch. The blended microparticles had lower dissolution in water than those of SF and starch microparticles. The 1/3 (w/w) SF/starch blended microparticles exhibited the lowest dissolution. The SF and starch microparticles showed irregular and deflated shapes, respectively. The blended microparticles were nearly spherical in shapes and smaller sizes. Thermal stability of the blended microparticles slightly increased with the starch blended ratio. The results suggested that SF conformational transition, thermal stability, morphology and dissolution of the blended microparticles can be adjusted by varying the blended ratio.
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institution Kabale University
issn 1788-618X
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publishDate 2010-12-01
publisher Budapest University of Technology and Economics
record_format Article
series eXPRESS Polymer Letters
spelling doaj-art-9a372885f98d45c4807d2014cbf8478f2025-08-20T03:33:46ZengBudapest University of Technology and EconomicseXPRESS Polymer Letters1788-618X2010-12-0141278178910.3144/expresspolymlett.2010.94Morphology and thermal stability of silk fibroin/starch blended microparticlesIn the present study biodegradable microparticles of silk fibroin (SF)/starch blends were prepared by a simple water-in-oil emulsion solvent diffusion technique. SF/starch blended solution and ethyl acetate were used as water and oil phases, respectively. The influence of SF/starch ratios on characteristics of the blended microparticles was investigated. The SF conformation of microparticle matrices from FTIR analysis was changed from random coil to β-sheet form by blending with starch. The blended microparticles had lower dissolution in water than those of SF and starch microparticles. The 1/3 (w/w) SF/starch blended microparticles exhibited the lowest dissolution. The SF and starch microparticles showed irregular and deflated shapes, respectively. The blended microparticles were nearly spherical in shapes and smaller sizes. Thermal stability of the blended microparticles slightly increased with the starch blended ratio. The results suggested that SF conformational transition, thermal stability, morphology and dissolution of the blended microparticles can be adjusted by varying the blended ratio.http://www.expresspolymlett.com/letolt.php?file=EPL-0001683&mi=cdBiopolymers, biocompositessilk fibroinstarchmorphologythermal properties
spellingShingle Morphology and thermal stability of silk fibroin/starch blended microparticles
eXPRESS Polymer Letters
Biopolymers, biocomposites
silk fibroin
starch
morphology
thermal properties
title Morphology and thermal stability of silk fibroin/starch blended microparticles
title_full Morphology and thermal stability of silk fibroin/starch blended microparticles
title_fullStr Morphology and thermal stability of silk fibroin/starch blended microparticles
title_full_unstemmed Morphology and thermal stability of silk fibroin/starch blended microparticles
title_short Morphology and thermal stability of silk fibroin/starch blended microparticles
title_sort morphology and thermal stability of silk fibroin starch blended microparticles
topic Biopolymers, biocomposites
silk fibroin
starch
morphology
thermal properties
url http://www.expresspolymlett.com/letolt.php?file=EPL-0001683&mi=cd