Low-dose oral minoxidil in a case of short anagen syndrome
Purpose This study aims to explore the effectiveness of low-dose oral minoxidil (LDOM) in treating short anagen hair syndrome (SAS), a rare congenital condition characterized by a shortened anagen phase. While SAS often resolves spontaneously with puberty, treatment remains controversial. Recent stu...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
|
| Series: | Journal of Dermatological Treatment |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/09546634.2025.2460580 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1825206965628829696 |
|---|---|
| author | Divija Sharma Serena Morsia Benjamin Ungar |
| author_facet | Divija Sharma Serena Morsia Benjamin Ungar |
| author_sort | Divija Sharma |
| collection | DOAJ |
| description | Purpose This study aims to explore the effectiveness of low-dose oral minoxidil (LDOM) in treating short anagen hair syndrome (SAS), a rare congenital condition characterized by a shortened anagen phase. While SAS often resolves spontaneously with puberty, treatment remains controversial. Recent studies have demonstrated the efficacy of low-dose oral minoxidil (LDOM) in treating various hair loss conditions, including SAS.Materials and methods This report presents a case of a 24-year-old female with SAS who experienced significant improvement following LDOM treatment. The patient, who had persistent hair growth issues since childhood, had tried several therapies, including topical 5% minoxidil with limited success. The patient was started on LDOM at 1.25 mg and increased to 2.5 mg after one month.Results After starting LDOM, the patient reported reduced hair shedding, increased hair length, and improved hair density, which was also confirmed by Canfield’s HairMetrix measurements. Despite experiencing mild facial hypertrichosis, the patient opted to continue the treatment.Conclusion This case adds to the growing body of evidence supporting LDOM as a viable treatment for adult SAS. The findings may also offer insights into the genetic basis of SAS and its overlap with other hair loss conditions, suggesting possible shared therapeutic approaches. |
| format | Article |
| id | doaj-art-9a36badd6348474382208c57a2b000f4 |
| institution | Kabale University |
| issn | 0954-6634 1471-1753 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Dermatological Treatment |
| spelling | doaj-art-9a36badd6348474382208c57a2b000f42025-02-07T00:47:26ZengTaylor & Francis GroupJournal of Dermatological Treatment0954-66341471-17532025-12-0136110.1080/09546634.2025.2460580Low-dose oral minoxidil in a case of short anagen syndromeDivija Sharma0Serena Morsia1Benjamin Ungar2Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USADepartment of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USADepartment of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USAPurpose This study aims to explore the effectiveness of low-dose oral minoxidil (LDOM) in treating short anagen hair syndrome (SAS), a rare congenital condition characterized by a shortened anagen phase. While SAS often resolves spontaneously with puberty, treatment remains controversial. Recent studies have demonstrated the efficacy of low-dose oral minoxidil (LDOM) in treating various hair loss conditions, including SAS.Materials and methods This report presents a case of a 24-year-old female with SAS who experienced significant improvement following LDOM treatment. The patient, who had persistent hair growth issues since childhood, had tried several therapies, including topical 5% minoxidil with limited success. The patient was started on LDOM at 1.25 mg and increased to 2.5 mg after one month.Results After starting LDOM, the patient reported reduced hair shedding, increased hair length, and improved hair density, which was also confirmed by Canfield’s HairMetrix measurements. Despite experiencing mild facial hypertrichosis, the patient opted to continue the treatment.Conclusion This case adds to the growing body of evidence supporting LDOM as a viable treatment for adult SAS. The findings may also offer insights into the genetic basis of SAS and its overlap with other hair loss conditions, suggesting possible shared therapeutic approaches.https://www.tandfonline.com/doi/10.1080/09546634.2025.2460580Alopeciashort anagen hair syndromelow dose oral minoxidilCanfield’s HairMetrixhair loss |
| spellingShingle | Divija Sharma Serena Morsia Benjamin Ungar Low-dose oral minoxidil in a case of short anagen syndrome Journal of Dermatological Treatment Alopecia short anagen hair syndrome low dose oral minoxidil Canfield’s HairMetrix hair loss |
| title | Low-dose oral minoxidil in a case of short anagen syndrome |
| title_full | Low-dose oral minoxidil in a case of short anagen syndrome |
| title_fullStr | Low-dose oral minoxidil in a case of short anagen syndrome |
| title_full_unstemmed | Low-dose oral minoxidil in a case of short anagen syndrome |
| title_short | Low-dose oral minoxidil in a case of short anagen syndrome |
| title_sort | low dose oral minoxidil in a case of short anagen syndrome |
| topic | Alopecia short anagen hair syndrome low dose oral minoxidil Canfield’s HairMetrix hair loss |
| url | https://www.tandfonline.com/doi/10.1080/09546634.2025.2460580 |
| work_keys_str_mv | AT divijasharma lowdoseoralminoxidilinacaseofshortanagensyndrome AT serenamorsia lowdoseoralminoxidilinacaseofshortanagensyndrome AT benjaminungar lowdoseoralminoxidilinacaseofshortanagensyndrome |