Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study

Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study

IntroductionOsteoarthritis (OA) is a progressive degenerative disease of synovial joints which is highly prevalent in dogs and results in lameness, loss of joint function and mobility, chronic pain, and reduced quality of life. Traditional OA management consist of non-steroidal anti-inflammatory dru...

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Main Authors: Vladimir Gabai, Evgeny Bakin, Maxim Langs, Robert Devlin, Sergei Krasny, Yauheni Baranou, Sergey Polyakov, Maksim Patapovich, Sergey Gvozdev, Maksim Kardash, Aliaksei Bazyleuski, Andrei Yeliseyeu, Egor Lelikov, Andrei Borodko, Alexander Shneider
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Veterinary Science
Subjects:
DNA plasmid
inflammation
chronic pain
pilot trial
safety
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2025.1519881/full
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