CCN5 Drives Leydig Cell Aging and Testicular Dysfunction: Insights into Fibrosis, Lipid Dysregulation, and Therapeutic Potential

CCN5 Drives Leydig Cell Aging and Testicular Dysfunction: Insights into Fibrosis, Lipid Dysregulation, and Therapeutic Potential

Leydig cells’ (LCs’) senescence is an important reason for the decline of testicular function in elderly men. Cellular communication network factor 5 (CCN5) regulates lipid metabolism and cellular fibrosis through multiple mechanisms. However, its role in LCs’ aging and the underlying molecular mech...

Full description

Saved in:
Bibliographic Details
Main Authors: Xiaoli Tan, Yanghua Xu, Ningjing Ou, Yuzhuo Chen, Wanyi Xia, Emily Xing, Ren Mo, Hao Bo, Zhitao Han, Jiarong Xu, Zepeng Dong, Yingbo Dai, Yuxin Tang, Liangyu Zhao
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2025-01-01
Series:Research
Online Access:https://spj.science.org/doi/10.34133/research.0762
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items