Blood-borne immune cells carry low biomass DNA remnants of microbes in patients with colorectal cancer or inflammatory bowel disease

Blood-borne immune cells carry low biomass DNA remnants of microbes in patients with colorectal cancer or inflammatory bowel disease

The involvement of the intestinal microbiome in the pathogenesis of inflammatory bowel disease (IBD) and colorectal cancer (CRC), is well-established. Bacteria interact with immune cells at sites of intestinal inflammation, but also in the CRC tumor microenvironment. We hypothesized that bacterial r...

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Main Authors: Yasser Morsy, Åsa Walberg, Paulina Wawrzyniak, Barbara Hubeli, Luca Truscello, Celine Mamie, Ania Niechcial, Emilie Gueguen, Roberto Manzini, Claudia Gottier, Silvia Lang, Sylvie Scharl, Sena Blümel, Luc Biedermann, Gerhard Rogler, Matthias Turina, Michaela Ramser, Henrik Petrowsky, Isabelle C. Arnold, Sebastian Zeissig, Nicola Zamboni, Adrian Egli, Jan Hendrik Niess, Petr Hruz, Alexander Knuth, Ralph Fritsch, Markus G. Manz, Marcin Wawrzyniak, Michael Scharl
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
Microbiome
colorectal cancer metastasis
inflammatory bowel disease pathogenesis
cancer and microbiome
intestinal epithelial barrier defect
peripheral blood mononuclear cells
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2530157
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