Ciprofol suppresses glycolysis and EMT in colorectal cancer cells by activating APC to modulate the Wnt/β-catenin signaling pathway

Ciprofol suppresses glycolysis and EMT in colorectal cancer cells by activating APC to modulate the Wnt/β-catenin signaling pathway

Abstract Ciprofol, an innovative anesthetic derived from propofol, has not yet been studied in detail regarding its effects in colorectal cancer (CRC). This study mainly explored the effects of Ciprofol on the epithelial-mesenchymal transition (EMT) process, glycolysis, and the Wnt/β-catenin signali...

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Bibliographic Details
Main Authors:	Han Wu, Jiening Gao, Yong Wang, Yao Zhang, Li Jia, Weijing Li
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-07-01
Series:	Scientific Reports
Subjects:	Ciprofol Adenomatous polyposis coli Wnt/β-catenin signaling pathway Epithelial-mesenchymal transition Glycolysis
Online Access:	https://doi.org/10.1038/s41598-025-08652-5
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