The RNA-binding protein RRP1 brakes macrophage one-carbon metabolism to suppress autoinflammation

The RNA-binding protein RRP1 brakes macrophage one-carbon metabolism to suppress autoinflammation

Abstract RNA-binding proteins (RBP) are important for the initiation and resolution of inflammation, so better understanding of RBP-RNA interactions and their crosstalk with metabolism may provide alternate targets to controlling inflammation. Here we establish global RNA-protein interactome purific...

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Bibliographic Details
Main Authors: Yumei Zhou, Mengxuan Li, Ke Jin, Mingyue Wen, Hua Qin, Yue Xu, Chunmei Wang, Xuan Zhang, Xuetao Cao
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62173-3
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