Angioplasty and carotid artery stenting: clinical and morphological factors affecting long-term outcomes
Aim. To identify clinical and morphological factors affecting the longterm outcomes of endovascular angioplasty and carotid artery stenting.Material and methods. The analysis included 198 patients after carotid artery stenting between 03.2014 and 05.2018. There were following inclusion criteria: (1)...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
«SILICEA-POLIGRAF» LLC
2020-07-01
|
| Series: | Кардиоваскулярная терапия и профилактика |
| Subjects: | |
| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/2470 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849408509029908480 |
|---|---|
| author | F. B. Shukurov E. S. Bulgakova B. A. Rudenko N. E. Gavrilova T. V. Tvorogova A. S. Shanoyan A. Yu. Suvorov D. A. Feshchenko D. K. Vasiliev |
| author_facet | F. B. Shukurov E. S. Bulgakova B. A. Rudenko N. E. Gavrilova T. V. Tvorogova A. S. Shanoyan A. Yu. Suvorov D. A. Feshchenko D. K. Vasiliev |
| author_sort | F. B. Shukurov |
| collection | DOAJ |
| description | Aim. To identify clinical and morphological factors affecting the longterm outcomes of endovascular angioplasty and carotid artery stenting.Material and methods. The analysis included 198 patients after carotid artery stenting between 03.2014 and 05.2018. There were following inclusion criteria: (1) 50% of symptomatic or 70% of asymptomatic carotid artery stenosis of according to NASCET (North American Symptomatic Carotid Endarterectomy Trial) criteria; (2) follow-up for each patient for at least 1 year. Using the univariate and multivariate logistic regression, risk factors associated with adverse events were determined.Results. The incidence of major adverse events during the 12-month follow-up was 9,6% (n=19), including 4 (2%) major and 6 (3%) minor strokes, 7 (3,5%) cases of transient ischemic attack; one (0,5%) patient had transient blindness and one (0,5%) died in the long-term follow-up period due to acute cerebrovascular accident in the target arterial territory. Also, 11 (5,6%) patients had restenosis >50% after 12-month follow-up. Multivariate analysis showed that long-term outcomes were significantly affected by: age >70 years (odds ratio (OR)=1,27, 95% confidence interval (CI): 1,07-1,61 (p=0,01); using of open-cell stents (OR=1,02, 95% CI: 1,01-1,03 (p=0,034)); contralateral stenosis (OR=1,28, 95% CI: 1,05-1,57 (p=0,01); lesion length >15 mm (OR=1,46, 95% CI: 1,12-1,89 (p=0,01)); residual stenosis <30% (OR=1,38, 95% CI: 1,09-1,49 (p=0,012)); complicated atherosclerotic plaque (OR=1,78, 95% CI: 1,21- 2,34 (p=0,007)). The development of in-stent restenosis was significantly influenced by factors such as the residual stenosis ><30% (OR=1,26, 95% CI: 1,1-1,65; p=0,017) and severe plaque calcification (OR=1,24, 95% CI: 1,04-1,31; p=0,02). Conclusion. The results obtained indicate the need for more careful preparation for endovascular intervention. Such factors as the use of open-cell stents, contralateral stenosis, lesion length >< 30% (OR=1,38, 95% CI: 1,09-1,49 (p=0,012)); complicated atherosclerotic plaque (OR=1,78, 95% CI: 1,21- 2,34 (p=0,007)). The development of in-stent restenosis was significantly influenced by factors such as the residual stenosis <30% (OR=1,26, 95% CI: 1,1-1,65; p=0,017) and severe plaque calcification (OR=1,24, 95% CI: 1,04-1,31; p=0,02).Conclusion. The results obtained indicate the need for more careful preparation for endovascular intervention. Such factors as the use of open-cell stents, contralateral stenosis, lesion length >15 mm, and residual stenosis < 30% may be associated with an increased risk of adverse events. |
| format | Article |
| id | doaj-art-9a147e16275f416cabdd4eea912cc8bf |
| institution | Kabale University |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2020-07-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-9a147e16275f416cabdd4eea912cc8bf2025-08-20T03:35:46Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252020-07-0119310.15829/1728-8800-2020-24702087Angioplasty and carotid artery stenting: clinical and morphological factors affecting long-term outcomesF. B. Shukurov0E. S. Bulgakova1B. A. Rudenko2N. E. Gavrilova3T. V. Tvorogova4A. S. Shanoyan5A. Yu. Suvorov6D. A. Feshchenko7D. K. Vasiliev8National Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineSem’ya Clinic. LobnyaNational Medical Research Center for Therapy and Preventive MedicineCity Clinical Hospital № 4National Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineAim. To identify clinical and morphological factors affecting the longterm outcomes of endovascular angioplasty and carotid artery stenting.Material and methods. The analysis included 198 patients after carotid artery stenting between 03.2014 and 05.2018. There were following inclusion criteria: (1) 50% of symptomatic or 70% of asymptomatic carotid artery stenosis of according to NASCET (North American Symptomatic Carotid Endarterectomy Trial) criteria; (2) follow-up for each patient for at least 1 year. Using the univariate and multivariate logistic regression, risk factors associated with adverse events were determined.Results. The incidence of major adverse events during the 12-month follow-up was 9,6% (n=19), including 4 (2%) major and 6 (3%) minor strokes, 7 (3,5%) cases of transient ischemic attack; one (0,5%) patient had transient blindness and one (0,5%) died in the long-term follow-up period due to acute cerebrovascular accident in the target arterial territory. Also, 11 (5,6%) patients had restenosis >50% after 12-month follow-up. Multivariate analysis showed that long-term outcomes were significantly affected by: age >70 years (odds ratio (OR)=1,27, 95% confidence interval (CI): 1,07-1,61 (p=0,01); using of open-cell stents (OR=1,02, 95% CI: 1,01-1,03 (p=0,034)); contralateral stenosis (OR=1,28, 95% CI: 1,05-1,57 (p=0,01); lesion length >15 mm (OR=1,46, 95% CI: 1,12-1,89 (p=0,01)); residual stenosis <30% (OR=1,38, 95% CI: 1,09-1,49 (p=0,012)); complicated atherosclerotic plaque (OR=1,78, 95% CI: 1,21- 2,34 (p=0,007)). The development of in-stent restenosis was significantly influenced by factors such as the residual stenosis ><30% (OR=1,26, 95% CI: 1,1-1,65; p=0,017) and severe plaque calcification (OR=1,24, 95% CI: 1,04-1,31; p=0,02). Conclusion. The results obtained indicate the need for more careful preparation for endovascular intervention. Such factors as the use of open-cell stents, contralateral stenosis, lesion length >< 30% (OR=1,38, 95% CI: 1,09-1,49 (p=0,012)); complicated atherosclerotic plaque (OR=1,78, 95% CI: 1,21- 2,34 (p=0,007)). The development of in-stent restenosis was significantly influenced by factors such as the residual stenosis <30% (OR=1,26, 95% CI: 1,1-1,65; p=0,017) and severe plaque calcification (OR=1,24, 95% CI: 1,04-1,31; p=0,02).Conclusion. The results obtained indicate the need for more careful preparation for endovascular intervention. Such factors as the use of open-cell stents, contralateral stenosis, lesion length >15 mm, and residual stenosis < 30% may be associated with an increased risk of adverse events.https://cardiovascular.elpub.ru/jour/article/view/2470carotid artery atherosclerosisstentingrestenosiscalcification |
| spellingShingle | F. B. Shukurov E. S. Bulgakova B. A. Rudenko N. E. Gavrilova T. V. Tvorogova A. S. Shanoyan A. Yu. Suvorov D. A. Feshchenko D. K. Vasiliev Angioplasty and carotid artery stenting: clinical and morphological factors affecting long-term outcomes Кардиоваскулярная терапия и профилактика carotid artery atherosclerosis stenting restenosis calcification |
| title | Angioplasty and carotid artery stenting: clinical and morphological factors affecting long-term outcomes |
| title_full | Angioplasty and carotid artery stenting: clinical and morphological factors affecting long-term outcomes |
| title_fullStr | Angioplasty and carotid artery stenting: clinical and morphological factors affecting long-term outcomes |
| title_full_unstemmed | Angioplasty and carotid artery stenting: clinical and morphological factors affecting long-term outcomes |
| title_short | Angioplasty and carotid artery stenting: clinical and morphological factors affecting long-term outcomes |
| title_sort | angioplasty and carotid artery stenting clinical and morphological factors affecting long term outcomes |
| topic | carotid artery atherosclerosis stenting restenosis calcification |
| url | https://cardiovascular.elpub.ru/jour/article/view/2470 |
| work_keys_str_mv | AT fbshukurov angioplastyandcarotidarterystentingclinicalandmorphologicalfactorsaffectinglongtermoutcomes AT esbulgakova angioplastyandcarotidarterystentingclinicalandmorphologicalfactorsaffectinglongtermoutcomes AT barudenko angioplastyandcarotidarterystentingclinicalandmorphologicalfactorsaffectinglongtermoutcomes AT negavrilova angioplastyandcarotidarterystentingclinicalandmorphologicalfactorsaffectinglongtermoutcomes AT tvtvorogova angioplastyandcarotidarterystentingclinicalandmorphologicalfactorsaffectinglongtermoutcomes AT asshanoyan angioplastyandcarotidarterystentingclinicalandmorphologicalfactorsaffectinglongtermoutcomes AT ayusuvorov angioplastyandcarotidarterystentingclinicalandmorphologicalfactorsaffectinglongtermoutcomes AT dafeshchenko angioplastyandcarotidarterystentingclinicalandmorphologicalfactorsaffectinglongtermoutcomes AT dkvasiliev angioplastyandcarotidarterystentingclinicalandmorphologicalfactorsaffectinglongtermoutcomes |