Neutrophil hypersegmentation and thrombocytosis in children with iron deficiency anemia
Neutrophil hypersegmentation is an expected peripheral blood smear finding in megaloblastic anemias. But some clinical reports suggest that neutrophil hypersegmentation may also occur in patients with iron deficiency anemia. In this study we searched the presence of neutrophil hypersegmentati...
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| Format: | Article |
| Language: | English |
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Hacettepe University Institute of Child Health
2005-07-01
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| Series: | The Turkish Journal of Pediatrics |
| Online Access: | https://turkjpediatr.org/article/view/2723 |
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| author | Serpil Düzgün Yildiz Yildirmak Feyzullah Cetinkaya |
| author_facet | Serpil Düzgün Yildiz Yildirmak Feyzullah Cetinkaya |
| author_sort | Serpil Düzgün |
| collection | DOAJ |
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Neutrophil hypersegmentation is an expected peripheral blood smear finding in megaloblastic anemias. But some clinical reports suggest that neutrophil hypersegmentation may also occur in patients with iron deficiency anemia. In this study we searched the presence of neutrophil hypersegmentation and thrombocytosis in patients with iron deficiency anemia but who had normal serum vitamin B12 and folic acid levels. The study comprised 102 patients with iron deficiency anemia and 21 age-matched healthy controls. All routine tests for iron deficiency anemia were done, serum folate and cobalamin levels were measured, and platelets were counted in all patients and controls. Peripheral blood smears were examined for neutrophil hypersegmentation. Hypersegmentation was found in 30.4% of anemic patients and in 9.5% of controls (p < 0.05). The number of platelets was also significantly higher in anemic children (p < 0.05). These results show that neutrophil hypersegmentation may also be seen in patients with iron deficiency anemia, and thrombocytosis is a common laboratory finding in this disorder.
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| format | Article |
| id | doaj-art-9a1251fcefc648d09f0c4346ca96d2a4 |
| institution | DOAJ |
| issn | 0041-4301 2791-6421 |
| language | English |
| publishDate | 2005-07-01 |
| publisher | Hacettepe University Institute of Child Health |
| record_format | Article |
| series | The Turkish Journal of Pediatrics |
| spelling | doaj-art-9a1251fcefc648d09f0c4346ca96d2a42025-08-20T02:55:39ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212005-07-01473Neutrophil hypersegmentation and thrombocytosis in children with iron deficiency anemiaSerpil Düzgün0Yildiz YildirmakFeyzullah CetinkayaSişli Etfal Education and Research Hospital, Istanbul, Turkey. Neutrophil hypersegmentation is an expected peripheral blood smear finding in megaloblastic anemias. But some clinical reports suggest that neutrophil hypersegmentation may also occur in patients with iron deficiency anemia. In this study we searched the presence of neutrophil hypersegmentation and thrombocytosis in patients with iron deficiency anemia but who had normal serum vitamin B12 and folic acid levels. The study comprised 102 patients with iron deficiency anemia and 21 age-matched healthy controls. All routine tests for iron deficiency anemia were done, serum folate and cobalamin levels were measured, and platelets were counted in all patients and controls. Peripheral blood smears were examined for neutrophil hypersegmentation. Hypersegmentation was found in 30.4% of anemic patients and in 9.5% of controls (p < 0.05). The number of platelets was also significantly higher in anemic children (p < 0.05). These results show that neutrophil hypersegmentation may also be seen in patients with iron deficiency anemia, and thrombocytosis is a common laboratory finding in this disorder. https://turkjpediatr.org/article/view/2723 |
| spellingShingle | Serpil Düzgün Yildiz Yildirmak Feyzullah Cetinkaya Neutrophil hypersegmentation and thrombocytosis in children with iron deficiency anemia The Turkish Journal of Pediatrics |
| title | Neutrophil hypersegmentation and thrombocytosis in children with iron deficiency anemia |
| title_full | Neutrophil hypersegmentation and thrombocytosis in children with iron deficiency anemia |
| title_fullStr | Neutrophil hypersegmentation and thrombocytosis in children with iron deficiency anemia |
| title_full_unstemmed | Neutrophil hypersegmentation and thrombocytosis in children with iron deficiency anemia |
| title_short | Neutrophil hypersegmentation and thrombocytosis in children with iron deficiency anemia |
| title_sort | neutrophil hypersegmentation and thrombocytosis in children with iron deficiency anemia |
| url | https://turkjpediatr.org/article/view/2723 |
| work_keys_str_mv | AT serpilduzgun neutrophilhypersegmentationandthrombocytosisinchildrenwithirondeficiencyanemia AT yildizyildirmak neutrophilhypersegmentationandthrombocytosisinchildrenwithirondeficiencyanemia AT feyzullahcetinkaya neutrophilhypersegmentationandthrombocytosisinchildrenwithirondeficiencyanemia |