Biofluorescence imaging system (BIS) Guided surgery for MRONJ: A Case Series on the Preservation of Teeth and Implants
The decision of surgical margin for Medication-Related Osteonecrosis of the Jaw (MRONJ) surgery is challenging. Recently, a method involving biofluorescence imaging system (BIS) has been reported for its application in MRONJ surgery to live detection of pathologic bone tissue from vital bone, which...
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Elsevier
2024-12-01
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| Series: | Photodiagnosis and Photodynamic Therapy |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1572100024004071 |
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| author | Sang-Hee Park Yesel Kim Hong-Cheol Yoon Pil-Young Yun Jeong-Kui Ku |
| author_facet | Sang-Hee Park Yesel Kim Hong-Cheol Yoon Pil-Young Yun Jeong-Kui Ku |
| author_sort | Sang-Hee Park |
| collection | DOAJ |
| description | The decision of surgical margin for Medication-Related Osteonecrosis of the Jaw (MRONJ) surgery is challenging. Recently, a method involving biofluorescence imaging system (BIS) has been reported for its application in MRONJ surgery to live detection of pathologic bone tissue from vital bone, which cannot be distinguished during conventional surgery. This case series aimed to assess the outcomes of adjacent teeth and implants near the lesion site in MRONJ patients who underwent BIS-guided MRONJ surgery. This retrospective study was assessed the radiographic and clinical outcomes of seven patients who underwent MRONJ surgery with BIS guidance but chose not to remove adjacent teeth or implants near the lesion. A total of seven patients (1 male, 6 females, 77.2 ± 4.7 years) were included in the study. Four implants and four teeth adjacent to the lesion were preserved. Over an average duration of 8.7 months, all subjects exhibited normal soft tissue healing and function without any complications. In conclusion, the BIS guided MRONJ surgery can be considered a minimally invasive and effective approach. |
| format | Article |
| id | doaj-art-9a0d8900958c4c368f79ec2f496ed4b0 |
| institution | OA Journals |
| issn | 1572-1000 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Photodiagnosis and Photodynamic Therapy |
| spelling | doaj-art-9a0d8900958c4c368f79ec2f496ed4b02025-08-20T01:59:30ZengElsevierPhotodiagnosis and Photodynamic Therapy1572-10002024-12-015010437010.1016/j.pdpdt.2024.104370Biofluorescence imaging system (BIS) Guided surgery for MRONJ: A Case Series on the Preservation of Teeth and ImplantsSang-Hee Park0Yesel Kim1Hong-Cheol Yoon2Pil-Young Yun3Jeong-Kui Ku4Department of Oral and Maxillofacial Surgery, Jeonbuk Nation University Dental Hospital, 20, Geonji-ro, Deokjin-gu, Jeonju-si, Jeonbuk-do, 54907, Republic of KoreaDepartment of Dental Hygiene, Jeonju Kijeon College, Jeonju 54989, Republic of KoreaBESTDEN Dental Clinic, 110 Teheran-ro 4F(Cambridge B/D), Gangnam-gu, Seoul, 06232, Republic of KoreaDepartment of Oral and Maxillofacial Surgery, Seoul National University Bundang Hospital, Bundang-gu, Seongnam-si, Republic of Korea; Department of Dentistry and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of KoreaDepartment of Oral and Maxillofacial Surgery, Jeonbuk Nation University Dental Hospital, 20, Geonji-ro, Deokjin-gu, Jeonju-si, Jeonbuk-do, 54907, Republic of Korea; Department of Oral and Maxillofacial Surgery, Seoul National University Bundang Hospital, Bundang-gu, Seongnam-si, Republic of Korea; Corresponding author at: Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, 172, Dolma-ro, Bundang-gu, Seongnam-si, Gyeonggi-do, 13605, Republic of Korea.The decision of surgical margin for Medication-Related Osteonecrosis of the Jaw (MRONJ) surgery is challenging. Recently, a method involving biofluorescence imaging system (BIS) has been reported for its application in MRONJ surgery to live detection of pathologic bone tissue from vital bone, which cannot be distinguished during conventional surgery. This case series aimed to assess the outcomes of adjacent teeth and implants near the lesion site in MRONJ patients who underwent BIS-guided MRONJ surgery. This retrospective study was assessed the radiographic and clinical outcomes of seven patients who underwent MRONJ surgery with BIS guidance but chose not to remove adjacent teeth or implants near the lesion. A total of seven patients (1 male, 6 females, 77.2 ± 4.7 years) were included in the study. Four implants and four teeth adjacent to the lesion were preserved. Over an average duration of 8.7 months, all subjects exhibited normal soft tissue healing and function without any complications. In conclusion, the BIS guided MRONJ surgery can be considered a minimally invasive and effective approach.http://www.sciencedirect.com/science/article/pii/S1572100024004071Diagnostic imagingMinimally invasive surgical proceduresMedication-related osteonecrosis of jawPrognosisQuantitative light-induced fluorescenceOsteonecrosis |
| spellingShingle | Sang-Hee Park Yesel Kim Hong-Cheol Yoon Pil-Young Yun Jeong-Kui Ku Biofluorescence imaging system (BIS) Guided surgery for MRONJ: A Case Series on the Preservation of Teeth and Implants Photodiagnosis and Photodynamic Therapy Diagnostic imaging Minimally invasive surgical procedures Medication-related osteonecrosis of jaw Prognosis Quantitative light-induced fluorescence Osteonecrosis |
| title | Biofluorescence imaging system (BIS) Guided surgery for MRONJ: A Case Series on the Preservation of Teeth and Implants |
| title_full | Biofluorescence imaging system (BIS) Guided surgery for MRONJ: A Case Series on the Preservation of Teeth and Implants |
| title_fullStr | Biofluorescence imaging system (BIS) Guided surgery for MRONJ: A Case Series on the Preservation of Teeth and Implants |
| title_full_unstemmed | Biofluorescence imaging system (BIS) Guided surgery for MRONJ: A Case Series on the Preservation of Teeth and Implants |
| title_short | Biofluorescence imaging system (BIS) Guided surgery for MRONJ: A Case Series on the Preservation of Teeth and Implants |
| title_sort | biofluorescence imaging system bis guided surgery for mronj a case series on the preservation of teeth and implants |
| topic | Diagnostic imaging Minimally invasive surgical procedures Medication-related osteonecrosis of jaw Prognosis Quantitative light-induced fluorescence Osteonecrosis |
| url | http://www.sciencedirect.com/science/article/pii/S1572100024004071 |
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