Menopausal transition alters female skeletal muscle transcriptome

Menopausal transition alters female skeletal muscle transcriptome

Although skeletal muscle is a target of hormonal regulation, the muscle transcriptome, including messenger-RNA (mRNA), long non-coding RNAs (lncRNAs), and microRNAs (miRNAs) has not previously been studied across the menopausal transition. Thus, we took a multi-RNA-omics approach to get insight into...

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Main Authors: Juppi Hanna-Kaarina, Korhonen Tia-Marje, Sievänen Tero, Kovanen Vuokko, Kujala Urho M., Aukee Pauliina, Cronin Neil, Sipilä Sarianna, Karvinen Sira, Laakkonen Eija K.
Format: Article
Language:English
Published: De Gruyter 2024-03-01
Series:Translational Exercise Biomedicine
Subjects:
estrogen
menopause
muscle transcriptome
female physiology
non-coding rna
multi-omics
Online Access:https://doi.org/10.1515/teb-2024-2001
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Summary:Although skeletal muscle is a target of hormonal regulation, the muscle transcriptome, including messenger-RNA (mRNA), long non-coding RNAs (lncRNAs), and microRNAs (miRNAs) has not previously been studied across the menopausal transition. Thus, we took a multi-RNA-omics approach to get insight into transcriptome-wide events of menopause.
ISSN:2942-6812

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