Utility of FDG PET/CT in Sjögren’s Syndrome and associated lymphomas; Lymphomagenesis

Primary Sjögren syndrome (SS) is an autoimmune disease affecting exocrine glands, with predisposition to development of lymphoma (lymphomagenesis). We report a case of Sjogren’s syndrome and discuss the role of FDG PET/CT in the primary diagnosis of lymphoma transformation in SS. Furthermore, we rev...

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Main Authors: Dikhra Khan, Prateek Kaushik, Sambit Sagar, Jasim Jaleel
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-01-01
Series:Asia Oceania Journal of Nuclear Medicine and Biology
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Online Access:https://aojnmb.mums.ac.ir/article_24351_b2ad07bef198f6d97c914485e6c5d58b.pdf
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author Dikhra Khan
Prateek Kaushik
Sambit Sagar
Jasim Jaleel
author_facet Dikhra Khan
Prateek Kaushik
Sambit Sagar
Jasim Jaleel
author_sort Dikhra Khan
collection DOAJ
description Primary Sjögren syndrome (SS) is an autoimmune disease affecting exocrine glands, with predisposition to development of lymphoma (lymphomagenesis). We report a case of Sjogren’s syndrome and discuss the role of FDG PET/CT in the primary diagnosis of lymphoma transformation in SS. Furthermore, we reviewed the literature regarding the utility of FDG PET/CT to assess systemic disease activity and also its role in the SS associated lymphoma with light into the new PET tracers that can be explored for these indications in the future.  Published data suggest promising role of FDG PET/CT in SS associated lymphomas, and demands larger studies for its establishment.
format Article
id doaj-art-9a037fb7efef40f8ab7fa0a385dff67d
institution OA Journals
issn 2322-5718
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language English
publishDate 2025-01-01
publisher Mashhad University of Medical Sciences
record_format Article
series Asia Oceania Journal of Nuclear Medicine and Biology
spelling doaj-art-9a037fb7efef40f8ab7fa0a385dff67d2025-08-20T02:38:03ZengMashhad University of Medical SciencesAsia Oceania Journal of Nuclear Medicine and Biology2322-57182322-57262025-01-0113110210610.22038/aojnmb.2024.76893.154124351Utility of FDG PET/CT in Sjögren’s Syndrome and associated lymphomas; LymphomagenesisDikhra Khan0Prateek Kaushik1Sambit Sagar2Jasim Jaleel3India Department Of Nuclear Medicine All India Institute of Medical Sciences, Delhi, IndiaIndia Department Of Nuclear Medicine All India Institute of Medical Sciences, Delhi, IndiaIndia Department Of Nuclear Medicine All India Institute of Medical Sciences, Delhi, IndiaAssistant Professor,Department of Nuclear Medicine,, Institute of Liver and Biliary Sciences, New Delhi, Delhi, India.Primary Sjögren syndrome (SS) is an autoimmune disease affecting exocrine glands, with predisposition to development of lymphoma (lymphomagenesis). We report a case of Sjogren’s syndrome and discuss the role of FDG PET/CT in the primary diagnosis of lymphoma transformation in SS. Furthermore, we reviewed the literature regarding the utility of FDG PET/CT to assess systemic disease activity and also its role in the SS associated lymphoma with light into the new PET tracers that can be explored for these indications in the future.  Published data suggest promising role of FDG PET/CT in SS associated lymphomas, and demands larger studies for its establishment.https://aojnmb.mums.ac.ir/article_24351_b2ad07bef198f6d97c914485e6c5d58b.pdfprimary sjögren syndromelymphomalymphomagenesisfdgpet/ct
spellingShingle Dikhra Khan
Prateek Kaushik
Sambit Sagar
Jasim Jaleel
Utility of FDG PET/CT in Sjögren’s Syndrome and associated lymphomas; Lymphomagenesis
Asia Oceania Journal of Nuclear Medicine and Biology
primary sjögren syndrome
lymphoma
lymphomagenesis
fdg
pet/ct
title Utility of FDG PET/CT in Sjögren’s Syndrome and associated lymphomas; Lymphomagenesis
title_full Utility of FDG PET/CT in Sjögren’s Syndrome and associated lymphomas; Lymphomagenesis
title_fullStr Utility of FDG PET/CT in Sjögren’s Syndrome and associated lymphomas; Lymphomagenesis
title_full_unstemmed Utility of FDG PET/CT in Sjögren’s Syndrome and associated lymphomas; Lymphomagenesis
title_short Utility of FDG PET/CT in Sjögren’s Syndrome and associated lymphomas; Lymphomagenesis
title_sort utility of fdg pet ct in sjogren s syndrome and associated lymphomas lymphomagenesis
topic primary sjögren syndrome
lymphoma
lymphomagenesis
fdg
pet/ct
url https://aojnmb.mums.ac.ir/article_24351_b2ad07bef198f6d97c914485e6c5d58b.pdf
work_keys_str_mv AT dikhrakhan utilityoffdgpetctinsjogrenssyndromeandassociatedlymphomaslymphomagenesis
AT prateekkaushik utilityoffdgpetctinsjogrenssyndromeandassociatedlymphomaslymphomagenesis
AT sambitsagar utilityoffdgpetctinsjogrenssyndromeandassociatedlymphomaslymphomagenesis
AT jasimjaleel utilityoffdgpetctinsjogrenssyndromeandassociatedlymphomaslymphomagenesis